Results 111 to 120 of about 323,113 (338)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Entretien avec Marie Cardinal : une femme et l’écriture
Cardinal Marie, Lévy-Delpla Laurence. Entretien avec Marie Cardinal : une femme et l’écriture. In: Diplômées, n°110, 1979. pp.
Cardinal, Marie, Lévy-Delpla, Laurence
core +1 more source
Godin describes Cardinal-Schubert's work as an exploration of the history of North American Native peoples in southwest Alberta. Cardinal-Schubert considers her work as an attempt to preserve an invisible culture. Biographical notes.
Godin, Deborah, Cardinal-Schubert, Joane
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
For each natural number $n$, let $C^{(n)}$ be the closed and unbounded proper class of ordinals $α$ such that $V_α$ is a $Σ_n$ elementary substructure of $V$. We say that $κ$ is a \emph{$C^{(n)}$-cardinal} if it is the critical point of an elementary embedding $j:V\to M$, $M$ transitive, with $j(κ)$ in $C^{(n)}$.
openaire +4 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Computing and managing cardinal direction relations
—Qualitative spatial reasoning forms an important part of the commonsense reasoning required for building intelligent Geographical Information Systems (GIS).
Skiadopoulos, S +11 more
core +1 more source
Sleep hygiene encompasses behavioral and environmental practices that shape sleep quality and circadian stability. Among young adults, lifestyle demands, academic pressures, and widespread digital media use contribute to irregular sleep–wake schedules ...
Patryk Romaniuk +8 more
doaj +1 more source

