Results 141 to 150 of about 323,113 (338)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Cardinal Life game scorecard

, 2009
This scorecard is for use with the "Cardinal Life game" also available from Cardinal Scholar from the GRMC. The board game can be accessed in Cardinal Scholar at http://cardinalscholar.bsu.edu/566/.

core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Real‐world practitioner perceptions of CARTITUDE‐4 results for patients with previously treated multiple myeloma

eJHaem
Introduction Initially approved for the fifth‐line or later therapeutic setting, the chimeric antigen receptor (CAR) T‐cell regimen ciltacabtagene autoleucel (cilta‐cel) was recently approved for second‐line (2L) treatment in relapsed/refractory multiple
Alexandrina Balanean, Samuel Baird, Brooke Dulka, Luke Jennings‐Zhang, Robert N. Bone, Yolaine Jeune‐Smith, Bruce Feinberg, Muhamed Baljevic   +7 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

York Region Administrative Centre

, 1988
General view of the secondary lobby; Newmarket's signature York Region Administrative Centre, a masonry-clad structure designed by Douglas Cardinal Architect Inc.
Cardinal, Douglas J.
core  

Indoor Environmental Quality (IEQ) in Healthcare Settings and Cognitive Performance of Staff

Journal of Education, Health and Sport
Introduction. Clinical work is performed under conditions of high cognitive load, time pressure and frequent interruptions. Research on patient safety has traditionally focused on sleep deprivation, fatigue and work organisation, whereas environmental ...
Michał Karol, Kamila Koseska, Jan Borowicz, Bartosz Górecki, Kinga Kloch, Patryk Romaniuk, Mariia-Khrystyna Lohin, Aleksandra Strawińska, Małgorzata Bednarczyk   +8 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Pat Cardinal interview

, 1975
9 p. transcript of an interview with Pat Cardinal conducted by Louis Rain, probably in 1975.
Cardinal, Pat, Rain, Louis
core  

Real-World Patient Characteristics, Treatment Patterns, and Clinical Outcomes in Patients with Relapsed or Refractory Multiple Myeloma Receiving Teclistamab: A Panel Chart Review Study

Oncology and Therapy
Introduction Teclistamab is an established standard of care for the treatment of relapsed/refractory multiple myeloma (RRMM) based on MajesTEC-1 study results.
Binod Dhakal, Moshe Y. Levy, Gilbert Ko, Jinghua He, Nina Kim, Wenze Tang, Tonya Le Blanc, Jessica Fowler, Sarah Lucht, Madison Brown, Emily Bland, Camryn Craig, Sarah Giegerich, JaLyna Laney, Bruce Feinberg, Niodita Gupta-Werner, Shuchita Kaila, Peter Voorhees   +17 more
doaj   +1 more source