Results 241 to 250 of about 561,316 (319)

LipidLocator: an open source Shiny web application for spatial lipidomics. [PDF]

Bioinform Adv
Arora P, Isfort S, Kirschke N, Masoodi M, Mercader N.   +4 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Assessment of the Effectiveness of Pharmaceutical Advice in Selected Digestive Disorders: Perspectives of Patients and Pharmacists as Part of a Pilot "Minor Ailments" Service. [PDF]

Diseases
Merks P, Religioni U, Vaillancourt R, Świetlik D, Plagens-Rotman K, Drelich E, Borowska M, Bromber P, Kaźmierczak J, Blicharska E, Piatkiewicz P, Królak-Ulińska A, Sierpiński R, Sikorski S, Doniec Z.   +14 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Mutant allele formation and inheritance during Cas9/guide RNA-mediated gene drive in a population modification mosquito strain for human malaria control. [PDF]

Genetics
Carballar-Lejarazú R, Pham TB, Tushar T, James AA.   +3 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Baffled? Not with 3D and 4D Flow

Journal of Cardiovascular Magnetic Resonance
Sara Santiaguel, MD, Laura Schoeneberg, MD, Ugonna Nwankwo, MD, Wilson King, MD   +3 more
doaj   +1 more source

Iconic number gestures: Naturalistic use by children and parents in the early home environment. [PDF]

Dev Psychol
Oswald M, Foley A, Goldin-Meadow S, Levine SC.   +3 more
europepmc   +1 more source

Sermon Notes of John Henry Cardinal Newman, 1849-1878

, 2001
John Henry Newman
openalex   +1 more source

Directed schemes of ideals and cardinal characteristics. I: The meager additive ideal

Miguel A. Cardona, Diego A. Mejía, Ismael E. Rivera-Madrid   +2 more
openalex   +1 more source