Results 271 to 280 of about 567,171 (329)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Vaginal Ulcers Secondary to Stage Iv Uterine Prolapse Treated With L-PRF. [PDF]

open access: yesClin Case Rep
Lucchina AG   +4 more
europepmc   +1 more source

3D MRI Biomarkers for Predicting Pelvic Organ Prolapse Risk and Severity. [PDF]

open access: yesInt Urogynecol J
Bai H   +5 more
europepmc   +1 more source

5- and 6-Membered Rings: A Natural Orbital Functional Study. [PDF]

open access: yesJ Chem Theory Comput
Mitxelena I, Lew-Yee JFH, Piris M.
europepmc   +1 more source

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