Results 51 to 60 of about 546,850 (281)
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Information, Entanglement, and Emergent Social Norms: Searching for ‘Normal’
SocietiesSocial norms are often regarded as informal rules or strategies. Previously, we have proposed that norms are better understood as information. Social norms represent a behavioral adaptation that identifies and curates the information required to create ...
James Scott Cardinal +1 more
doaj +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Organon F, 2019 The characteristic asymmetry in ascribing intentionality, known as the Knobe effect, is widely thought to result from the moral evaluation of the side effect.
Andrzej Waleszczyński +2 more
doaj +1 more source
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Acta Scientiarum: Biological Sciences, 2009 Os estudos sobre a parasitofauna de peixes ornamentais cultivados são de grande relevância para o conhecimento das espécies de parasitos, permitindo interferência em sua proliferação para evitar epizootias e, consequentemente, perdas econômicas na ...
Jefferson Raphael Gonzaga Lemos +2 more
doaj
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Theatrum Historiae, 2019 The paper aims to highlight the principal topics of Giovanni Botero’s speech Dell’uffizio del cardinale (1599), the first part of it being dedicated to show what cardinals could do to improve Catholicism in the Reformation world, and the second ...
Blythe Alice Raviola
doaj
The Foundations of Culture and the Moments of Social Information
HeritageDespite its foundational role in the social sciences, “culture” remains a persistently ambiguous concept. This is a perennial obstacle to communicating the broader value of our work to the public and policy-makers, and particularly in clarifying its ...
James Scott Cardinal +1 more
doaj +1 more source