Results 61 to 70 of about 561,316 (319)

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman   +17 more
wiley   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy   +5 more
wiley   +1 more source

Molecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk   +9 more
wiley   +1 more source

Protozoários e metazoários parasitos do cardinal Paracheirodon axelrodi Schultz, 1956 (Characidae), peixe ornamental proveniente de exportador de Manaus, Estado do Amazonas, Brasil = Protozoan and metazoan parasites of the cardinal Paracheirodon axelrodi Schultz, 1956 (Characidae), ornamental fish originating from exporter from Manaus, Amazonas State, Brazil

open access: yesActa Scientiarum: Biological Sciences, 2009
Os estudos sobre a parasitofauna de peixes ornamentais cultivados são de grande relevância para o conhecimento das espécies de parasitos, permitindo interferência em sua proliferação para evitar epizootias e, consequentemente, perdas econômicas na ...
Jefferson Raphael Gonzaga Lemos   +2 more
doaj  

Criterion‐Related Validity of the Neuropsychological Quick Assessment for Screening Cognitive, Motor, and Behavioral Impairments in Patients With Pediatric Brain Tumors: An Observational Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neuropsychological complications may impair the qualitative prognosis of patients with pediatric brain tumors. However, multifaceted evaluations cannot be conducted in all patients because they are time consuming and burdensome for patients.
Ami Tabata   +9 more
wiley   +1 more source

The Ideal Cardinal and the Role of the Papacy in Dell’uffizio del cardinale (1599) by Giovanni Botero

open access: yesTheatrum Historiae, 2019
The paper aims to highlight the principal topics of Giovanni Botero’s speech Dell’uffizio del cardinale (1599), the first part of it being dedicated to show what cardinals could do to improve Catholicism in the Reformation world, and the second ...
Blythe Alice Raviola
doaj  

The Foundations of Culture and the Moments of Social Information

open access: yesHeritage
Despite its foundational role in the social sciences, “culture” remains a persistently ambiguous concept. This is a perennial obstacle to communicating the broader value of our work to the public and policy-makers, and particularly in clarifying its ...
James Scott Cardinal   +1 more
doaj   +1 more source

The Significance of the Relationship between Main Effects and Side Effects for Understanding the Knobe Effect

open access: yesOrganon F, 2019
The characteristic asymmetry in ascribing intentionality, known as the Knobe effect, is widely thought to result from the moral evaluation of the side effect.
Andrzej Waleszczyński   +2 more
doaj   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson   +20 more
wiley   +1 more source

Orthostatic intolerance and presyncopal states in young adults

open access: yesJournal of Education, Health and Sport
Introduction and purpose: Orthostatic intolerance is an increasingly recognized disturbance of circulatory regulation in young adults, particularly in academic settings where characteristic lifestyle patterns promote autonomic imbalance. The aim of this
Michał Karol   +8 more
doaj   +1 more source

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