Results 191 to 200 of about 42,860 (295)
When delay costs a limb: Severe chronic osteomyelitis in a patient with intravenous drug use. [PDF]
Vieira LF +4 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Quantifying germination cardinal temperatures of ten forage legumes using non-linear regression models. [PDF]
Shi M +12 more
europepmc +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Peace Thoughts by Stephen Cardinal Kim Sou-Hwan
김수환은 이 땅에서 천주교가 박해를 받던 시절부터 천주교 신앙을 지켜온 유서 깊은 신앙가문의 후손이다. 김수환이 천주교 신부로 사제서품을 받은 시기는 한국전쟁으로 우리 민족의 고통이 극에 달해 있던 바로 그 때이었다. 일본과 독일에서 유학한 그는 그리스도교 사회론을 전공하였다. 김수환은 1987년 이전에는 주로 인권회복과 정의구현에 관심을 기울였으며, 정치적 민주화가 어느 정도 이루어진 1987년 이후에는 민족의 화해와 일치에 더 많은 관심을 가졌다.
박일영
core
Non-diagnostic stereotactic intracranial biopsies: a 15-year institutional experience. [PDF]
Himic V +14 more
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
This project explores the design of a rail-trail in the Midwest utilizing visual preference methods with ArcGIS and 3D visualization technologies. It has been found that visually preferred environments are more enjoyable, more frequently used places that
Fraley, Jennifer R.
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

