Results 81 to 90 of about 3,892,698 (243)

Effect of temperature and lactic acid bacteria on the surface growth of Geotrichum candidum

open access: yesCzech Journal of Food Sciences, 2011
The surface growth of Geotrichum candidum isolated from ewes' lump cheese was studied on pure agar medium and that inoculated with Lactobacillus rhamnosus GG and L. paracasei subsp. paracasei CCM 1753.
Anna Hudecová   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Entretien avec Marie Cardinal : une femme et l’écriture

open access: yes, 1979
Cardinal Marie, Lévy-Delpla Laurence. Entretien avec Marie Cardinal : une femme et l’écriture. In: Diplômées, n°110, 1979. pp.
Cardinal, Marie, Lévy-Delpla, Laurence
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Cardinal-Schubert

open access: yes, 1983
Godin describes Cardinal-Schubert's work as an exploration of the history of North American Native peoples in southwest Alberta. Cardinal-Schubert considers her work as an attempt to preserve an invisible culture. Biographical notes.
Godin, Deborah, Cardinal-Schubert, Joane
core   +1 more source

Pinning and Dynamics of Abrikosov Vortices, Crystalline Defects, and Problem of Critical Current Density in Monocrystals and Biaxially-Oriented YBa2Cu3O7−δ High-Temperature Superconductor Films

open access: yesУспехи физики металлов, 2000
One of the most important problems of high-temperature superconductors (HTSC) is considered — the problem of cardinal differences between the values of bulk pinning force and the critical current density in bulk and thin-film materials of high ...
V. M. Pan
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Evaluation of Linear and Nonlinear Regression Models to Describe Response of Germination to Temperature in Lentil (Lens culinaris Medik. ) [PDF]

open access: yesIkufīziyuluzhī-i Giyāhān-i Zirā̒ī, 2014
This study was carried out to determine the requirements of cardinal temperatures and biological hours for germination of lentil by using different linear and nonlinear regression models. To do this, a split plot experiment based on randomized completely
S Rahban   +3 more
doaj  

Computing and managing cardinal direction relations

open access: yes, 2005
—Qualitative spatial reasoning forms an important part of the commonsense reasoning required for building intelligent Geographical Information Systems (GIS).
Skiadopoulos, S   +11 more
core   +1 more source

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