Results 121 to 130 of about 611,997 (371)
Advanced Science, EarlyView.Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu +13 more
wiley +1 more source
Simulation‐based team‐training in acute stroke: Is it safe to speed up?
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 Abstract Background In acute ischemic stroke (AIS), rapid treatment with intravenous thrombolysis (IVT) is crucial for good clinical outcome. Weekly simulation‐based team‐training of the stroke treatment team was implemented, resulting in faster treatment times.
Liv Jorunn Høllesli +8 more
wiley +1 more source
Osborn Waves in a Severely Hypothermic Patient
Journal of Education and Teaching in Emergency Medicine, 2018 History of present illness: An 88-year-old female was found lying prone and unresponsive outside of her home with an unknown downtime. She was intubated in the field by medics and brought to the emergency department (ED).
James Elliot Karz, DO +2 more
doaj +1 more source
Advanced Science, EarlyView.This study highlights the critical role of IRF8 in the development of AAA. IRF8 activation promotes the differentiation of cDC1s, which in turn recruit and activate CD8+ T cells, contributing to aortic wall degradation. The study identifies the IRF8‐cDC1‐CD8+ T cell axis as a key pathway in AAA progression, offering new potential therapeutic targets to
Zhen Yuan +11 more
wiley +1 more source
Advanced Science, EarlyView.Canopy FGF signaling regulator 2 (CNPY2) which is contributed to ERS is upregulated in the renal tubules of patients with diabetic nephropathy (DN). Mechanistically, CNPY2 may regulate ferroptosis and MAM integrity in renal tubular epithelial cells through PERK/ATF4/CHAC1 pathway, thereby promoting the progression of DN.
Jingfang Chen +9 more
wiley +1 more source
Catheterization and Cardiovascular Interventions, Volume 100, Issue 7, Page 1273-1283, December 1, 2022., 2022 Abstract Objectives The long‐term data on the use of drug‐coated balloons (DCBs) for femoropopliteal atherosclerotic lesions in the real‐world setting are limited, even more so for racially and geographically distinct populations. The present analysis reports the 5‐year safety and effectiveness outcomes of a DCB in the Asian subset of the prospective ...
Young‐Guk Ko +7 more
wiley +1 more source