Results 121 to 130 of about 297,969 (261)

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman, Ana Kolevzon, Paige Siper, Tess Levy, Jeffrey M. Saland, Yitzchak Frank, Robert Rapaport, Kayla Kupietzky, William E. Bennett Jr, Bruce Gelb, Sandra Bedrosian Sermone, Alexander Kolevzon   +11 more
wiley   +1 more source

Metformin Inhibits Inflammation by Targeting the NLRP3 Inflammasome: Linking NF-κB/NEK7/AMPK Signaling to Mitochondrial Function

Journal of Inflammation Research
Dingyi Ning,1,2 Chenxin Jiang,1 Jiangyan Zeng,3 Fanyun Zeng,3 Xuehong Zheng,4 Panpan Xia,5 Yunkun Liu,4 Xin Huang,4 Deju Zhang,6 Xiao Liu,7 Jing Zhang,8 Peng Yu4 1Queen Mary School, Nanchang University, Nanchang, 330006, People’s Republic of China; 2The ...
Ning D, Jiang C, Zeng J, Zeng F, Zheng X, Xia P, Liu Y, Huang X, Zhang D, Liu X, Zhang J, Yu P   +11 more
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Refining a preclinical model of viral myocarditis in accordance with biotech standards

Animal Models and Experimental Medicine, EarlyView.
This study aimed to refine a murine model of Coxsackievirus B3‐induced myocarditis by integrating dietary and imaging innovations to improve animal welfare, data quality, and clinical applicability. The refined diet significantly reduced animal health burden, reduced weight loss, and stabilized blood glucose during development of cardiac inflammation ...
Jonas Stewen, Julia Riedesel, Juliane Stein, Brandon H. Greene, Svenja Rohde, Sonja Suess, Bjoern Keiner, Priya Panjwani, Padmapriya Ponnuswamy, Juan E. Camacho Londoño   +9 more
wiley   +1 more source

Predictive Value of Uric Acid-to-Albumin Ratio for Left Atrial Thrombus or Spontaneous Echo Contrast in Patients with Non-Valvular Atrial Fibrillation

Journal of Inflammation Research
Xiangzhu Meng,1,* Yuhang Wen,1,* Xiangying Wang,2,* Tesfaldet Habtemariam Hidru,1 Yuqi Tang,1 Yunlong Xia,1 Xiaolei Yang,1 Lianjun Gao1 1Department of Cardiology, Institute of Cardiovascular Diseases, The First Affiliated Hospital
Meng X, Wen Y, Wang X, Hidru TH, Tang Y, Xia Y, Yang X, Gao L   +7 more
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Chinese Expert Consensus on Microvascular Protection Strategy During Emergency Percutaneous Coronary Intervention Therapy in Patients With ST-elevation Myocardial Infarction

Cardiology Discovery
Microcirculatory dysfunction (CMD) typically occurs in patients with acute ST-segment elevation myocardial infarction during percutaneous coronary intervention, which is associated with more severe myocardial injury and a worse prognosis.
Chinese Society of Cardiology, Chinese Medical Association; Editorial Board of Chinese Journal of Cardiology
doaj   +1 more source

Neuroprotection after transient middle cerebral artery occlusion in male rats using kojic acid nanostructured lipid carriers: A behavioral, biochemical, and histological study on hippocampal CA1 region

Animal Models and Experimental Medicine, EarlyView.
This study demonstrates that kojic acid–loaded nanostructured lipid carriers (KA‐NLC) provide significant neuroprotection in a male rat model of middle cerebral artery occlusion (MCAO)–induced stroke. Treatment with KA‐NLCs reduced cerebral edema, improved motor and coordination balance and neurological scores, and enhanced spatial and avoidance memory.
Mobina Gheibi, Erfan Ghadirzadeh, Javid Tebyani, Seyedeh Mohadeseh Moyaedi, Khadijeh Khezri, Majid Saeedi, Ali Siahposht‐Khachaki, Narges Karimi, Melika Pourhossein, Shiva Shadi, Sasan Shafiei, Atena Sharifi‐Razavi   +11 more
wiley   +1 more source

Time-Weighted Cumulative High-Sensitivity C-Reactive Protein and Risk of Cardiac Conduction Block: Findings from a Prospective Cohort

Journal of Inflammation Research
Mo Zhang,1,2,* Dou Shi,1,* Yixiu Chen,2,3 Yicheng Liao,2,3 Zhihui Liu,2,3 Renjie Fu,2,3 Yufeng Bian,2,3 Shuohua Chen,2 Haiyan Zhao,2 Honghong He,2 Changhao Zu,2 Chunlu Liu,2 Hongqiu Huo,2 Shouling Wu,2 Yuntao Wu2 1Graduate School, Hebei ...
Zhang M, Shi D, Chen Y, Liao Y, Liu Z, Fu R, Bian Y, Chen S, Zhao H, He H, Zu C, Liu C, Huo H, Wu S, Wu Y   +14 more
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SPISE Index (Single-Point Insulin Sensitivity Estimator): A Long-Term Predictor of Recurrence in Elderly Patients with Atrial Fibrillation After Radiofrequency Ablation

Clinical Interventions in Aging
Zhen Wang,1,* Yilin Qu,2,* Hua Wang,1,* Xiao Liu1,* 1Cardiology Department, Yantai Yuhuangding Hospital, Affiliated with Qingdao University, Yantai, People’s Republic of China; 2Medical Record Information Department ...
Wang Z, Qu Y, Wang H, Liu X
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The future of education in Preventive Cardiology. A Statement of the European Association of Preventive Cardiology (EAPC) of the ESC.

In recent years, major advances in our understanding of risk factors implicated in the development of cardiovascular disease (CVD), in available tools for early detection of CVD, and in effective interventions to prevent subclinical or clinically ...
Frederix, Ines, Jones, Jennifer L, Gaber, M Hemmat, Wilhelm, Matthias, Biffi, Alessandro, Cavarretta, Elena, Halle, Martin, Davos, Constantinos H, Malhotra, Aneil, Papadakis, Michael, Koskinas, Konstantinos, Hansen, Dominique   +11 more
core   +1 more source

The Clinical Significance and Prognostic Value of Inflammatory Hematological Indices in Young Patients with Coronary Artery Disease

Journal of Inflammation Research
Jiayin Sun,1 Shuchang Qi,1 Meihuizi Yu,2 Sitong Lei,3 Wei Han,1 Sijing Wu,1 Yujie Zhou,1 Dongmei Shi1 1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing Key ...
Sun J, Qi S, Yu M, Lei S, Han W, Wu S, Zhou Y, Shi D   +7 more
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