Results 161 to 170 of about 992,651 (390)
Advanced Science, EarlyView.Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang +12 more
wiley +1 more source
BMJ, 1999 In assessing the ability to benefit from treatment, chronological age is less important than other factors concerned with the biological ageing process and the presence of associated disease.1 Any rationing because of limitation of health resources should be on the basis of assessed individual physiological ability to benefit, not on the basis of age ...
openaire +6 more sources
Advanced Science, EarlyView.Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng +9 more
wiley +1 more source
Retracted: Establishment of a Nomogram for Predicting Early Death in Viral Myocarditis
Cardiology Research and Practice, 2023 Cardiology Research and Practice
doaj +1 more source
Zdravniški Vestnik, 2017 Introduction: Patients with major or critical congenital heart disease (CHD) require surgical treatment or interventional cardiac catheterization during the first year or 28 days of life, respectively.
Zoltan Narancsik +2 more
doaj
Vital Cardiology: A New Outlook on the Prevention of Heart Failure [PDF]
, 1934 Bruce Williamson
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Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis
Advanced Science, EarlyView.Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan +13 more
wiley +1 more source
Advanced Science, EarlyView.This study introduces two orthogonal sequencing methods, CMD1‐Deaminase sequencing (CD‐seq) and CMD1‐TET bisulfite sequencing (CT‐seq), that enable direct, independent detection of 5mC. Using these approaches together with ACE‐seq or TAB‐seq for 5hmC identification, the study reveals a significant reduction in 5hmC, but not 5mC, in the hippocampus of ...
Zi‐Xin Wang +15 more
wiley +1 more source
Journal of the American College of Cardiology, 2019 S. Grundy +23 more
semanticscholar +1 more source