Results 111 to 120 of about 421,250 (298)

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman, Mathieu Félices, Bhaskar Pandurangavittal, Sanman Ghorpade, Caroline Easterbrook, Marcin Zabielski, Oscar Della Pasqua   +6 more
wiley   +1 more source

Should socioeconomic factors be considered as traditional risk factors for cardiovascular disease, as confounders, or as risk modifiers? [PDF]

, 2008
A large number of studies show that cardiovascular disease and its traditional risk factors are associated with socioeconomic conditions. However, their etiological role in the development of cardiovascular outcomes is not always well understood ...
De Vogli, R., Marmot, M.
core  

Trust first, concerns second: An international vignette study of older adults' preferences towards deprescribing statins

British Journal of Clinical Pharmacology, EarlyView.
Abstract This study investigated the attitudes and beliefs of older adults towards deprescribing statins in Australia, the United Kingdom and the United States, using an online, vignette‐based study. Presented with a hypothetical scenario in which a general practitioner advised stopping simvastatin, participants rated their level of agreement and ...
Sarah E. Vordenberg, Noelia Dulo, Carissa Bonner, Eliza Ferguson, Vincent D. Marshall, Kristie Rebecca Weir   +5 more
wiley   +1 more source

Electrocardiogram Features in Non-Cardiac Diseases: From Mechanisms to Practical Aspects

Journal of Multidisciplinary Healthcare
Alexandr Ceasovschih,1,2,* Victorița Șorodoc,1,2 Serghei Covantsev,3,* Anastasia Balta,1,2,* Jamol Uzokov,4,* Sergio E Kaiser,5 Abdallah Almaghraby,6 Cătălina Lionte,1,2 Cristian Stătescu,1,7 Radu A Sascău,1,7 ...
Ceasovschih A, Șorodoc V, Covantsev S, Balta A, Uzokov J, Kaiser SE, Almaghraby A, Lionte C, Stătescu C, Sascău RA, Onofrei V, Haliga RE, Stoica A, Bologa C, Ailoaei Ș, Şener YZ, Kounis NG, Șorodoc L   +17 more
doaj  

2024 Clinical practice guidelines for Acute coronary syndrome without ST segment elevation electrocardiogram

Российский кардиологический журнал
Russian Society of Cardiology (RSC)With the participation of: the Association of Cardiovascular Surgeons, the Russian Society of Emergency Medical Care, the Russian Association of Ultrasound Diagnostics Specialists in Medicine (RASUDM)Approved by the ...
O. V. Averkov, G. K. Harutyunyan, D. V. Duplyakov, E. V. Konstantinova, N. N. Nikulina, R. M. Shakhnovich, I. S. Yavelov, A. N. Yakovlev, S. A. Abugov, B. G. Alekyan, D. M. Aronov, M. V. Arkhipov, O. L. Barbarash, S. A. Boytsov, M. G. Bubnova, T. V. Vavilova, E. Yu. Vasilyeva, A. S. Galyavich, V. I. Ganyukov, S. R. Gilyarevsky, E. P. Golubev, E. Z. Golukhova, D. A. Zateyshchikov, Yu. A. Karpov, E. D. Kosmacheva, Yu. M. Lopatin, V. A. Markov, E. V. Merkulov, N. A. Novikova, E P. Panchenko, D. V. Pevzner, N. V. Pogosova, D. M. Prasol, A. V. Protopopov, D. V. Skrypnik, R. S. Tarasov, S. N. Tereshchenko, S. A. Ustyugov, A. V. Khripun, E. A. Tsebrovskaya, S. V. Shalaev, E. V. Shlyakhto, A. V. Shpektor, S. S. Yakushin   +43 more
doaj   +1 more source

Racial/Ethnic Differences in Cardiac Care: The Weight of the Evidence [PDF]

, 2002
A substantial and growing body of research indicates that race/ethnicity -- independent of clinical and socioeconomic factors -- continues to matter in the U.S. health care system.

core  

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Systolic ejection murmurs and the left ventricular outflow tract in boxer dogs [PDF]

, 2007
Turbulence of various genesis in the left ventricular outflow tract (LVOT) causes systolic ejection murmurs. The prevalence of murmurs in adult boxer dogs is 50-80%, the majority of which are of low intensity.
Höglund, Katja
core  

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

The Feasibility of Imaging Myocardial Ischemic/Reperfusion Injury Using \u3csup\u3e99m\u3c/sup\u3eTc-labeled Duramycin in a Porcine Model [PDF]

, 2015
When pathologically externalized, phosphatidylethanolamine (PE) is a potential surrogate marker for detecting tissue injuries. 99mTc-labeled duramycin is a peptide-based imaging agent that binds PE with high affinity and specificity.
Audi, Said H., Fang, Wei, Holly, Thomas A., Johnson, Steven E., Lee, Daniel C., Wang, Feng, Wang, Lei, Zhao, Ming, Zhu, Bao, Zhu, Haibo, Zimmer, Michael   +10 more
core   +1 more source