Results 141 to 150 of about 391,673 (354)

Macrophage Zc3h12c Limits Tissue Inflammation and Injury via Alternative Splicing of Pre‐mRNA

open access: yesAdvanced Science, EarlyView.
This work defines the context‐dependent function of Zc3h12c in macrophages using the Tnfrsf11a‐Cre system. It reveals Zc3h12c's dual mechanism—regulating RNA degradation and alternative splicing—with STAT1 as a key target. The findings elucidate a novel post‐transcriptional pathway and identify STAT1 isoforms as potential therapeutic targets for kidney
Chenyu Li   +14 more
wiley   +1 more source

Cardiovascular publications in 2013 in Turkey advanced in quantity alone

open access: yesTürk Kardiyoloji Derneği Arşivi, 2014
Turkey's institutions in cardiovascular medicine were evaluated regarding publication output in 2013 based on data available in the Web of Science. Only articles in fulltext and reviews appearing in source publications covered by the Science Citation ...
Altan Onat
doaj   +1 more source

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

open access: yesAdvanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng   +9 more
wiley   +1 more source

Personalized medicine—a modern approach for the diagnosis and management of hypertension [PDF]

open access: yes, 2017
The main goal of treating hypertension is to reduce blood pressure to physiological levels and thereby prevent risk of cardiovascular disease and hypertension-associated target organ damage.
Borghi, Claudio   +5 more
core   +1 more source

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

open access: yesAdvanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan   +13 more
wiley   +1 more source

Patient adherence, compliance, and perspectives on evolocumab for the management of resistant hypercholesterolemia

open access: yesPatient Preference and Adherence, 2018
Constantine E Kosmas,1 Delia Silverio,2 Julio Ovalle,2 Peter D Montan,2 Eliscer Guzman3 1Division of Cardiology, Department of Medicine, Mount Sinai Hospital, New York, NY, USA; 2Cardiology Clinic, Cardiology Unlimited, PC, New York, NY, USA; 3Division ...
Kosmas CE   +4 more
doaj  

Efficiency of the Guide Extension Catheter-Facilitated Tip-in Technique in the Recanalization of Coronary Chronic Total Occlusion

open access: yesJournal of Multidisciplinary Healthcare, 2023
You Zhou,* Lixiang Deng,* Zhe Wang,* Yiqing Hu, Zhangwei Chen, Hao Lu, Juying Qian, Junbo Ge Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University; National Clinical Research Center for ...
Zhou Y   +7 more
doaj  

The prevalence of alternative herbal medicine and nutritional complementary product intake in patients admitted to out-patient cardiology departments

open access: yesTürk Kardiyoloji Derneği Arşivi, 2013
Objectives: To detect the prevalence of alternative herbal medicine and nutritional complementary product intake in patients admitted to outpatient cardiology clinics and to determine demographic characteristics, comorbidities and medical properties of ...
Esra Gücük İpek   +5 more
doaj   +1 more source

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