Results 151 to 160 of about 391,673 (354)

Biodegradable Medical Implants: Reshaping Future Medical Practice

open access: yesAdvanced Science, EarlyView.
Biodegradable medical implants are transforming future healthcare by providing sustainable, biocompatible solutions that eliminate secondary removal procedures, enhancing patients’ physical and psychological comfort, and reducing economic burdens.
Bo Xia   +4 more
wiley   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

open access: yesAdvanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang   +12 more
wiley   +1 more source

Inclisiran: A New Strategy for LDL-C Lowering and Prevention of Atherosclerotic Cardiovascular Disease

open access: yesVascular Health and Risk Management, 2023
Michael S Albosta,1 Jelani K Grant,2 Pam Taub,3 Roger S Blumenthal,2 Seth S Martin,2 Erin D Michos2 1Internal Medicine Department, University of Miami Miller School of Medicine/ Jackson Memorial Hospital, Miami, FL, USA; 2Ciccarone Center for the ...
Albosta MS   +5 more
doaj  

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

open access: yesAdvanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song   +17 more
wiley   +1 more source

BACE2‐Induced Aberrant Lymphatic Network Aggravates the Local Inflammation in Arteriovenous Fistulas With Hyperphosphatemia

open access: yesAdvanced Science, EarlyView.
Vascular endothelial growth factor (VEGF)‐C secreted by Pi16+ fibro‐progenitors lays the foundation of lymphatic network in mouse arteriovenous fistulas (AVFs), whereas the elevated phosphate (Pi) in 5/6‐nephrectomy (Nx) mouse activates p‐ERK/p‐SP1/BACE2 pathway to generate additional soluble VEGFR‐3, which causes VEGF‐C unresponsiveness and defective ...
Kai Chen   +14 more
wiley   +1 more source

Electrocardiogram Features in Non-Cardiac Diseases: From Mechanisms to Practical Aspects

open access: yesJournal of Multidisciplinary Healthcare
Alexandr Ceasovschih,1,2,* Victorița Șorodoc,1,2 Serghei Covantsev,3,* Anastasia Balta,1,2,* Jamol Uzokov,4,* Sergio E Kaiser,5 Abdallah Almaghraby,6 Cătălina Lionte,1,2 Cristian Stătescu,1,7 Radu A Sascău,1,7 ...
Ceasovschih A   +17 more
doaj  

2024 Clinical practice guidelines for Acute coronary syndrome without ST segment elevation electrocardiogram

open access: yesРоссийский кардиологический журнал
Russian Society of Cardiology (RSC)With the participation of: the Association of Cardiovascular Surgeons, the Russian Society of Emergency Medical Care, the Russian Association of Ultrasound Diagnostics Specialists in Medicine (RASUDM)Approved by the ...
O. V. Averkov   +43 more
doaj   +1 more source

Knowledge, Attitude, and Practice on Atrial Fibrillation and Atrial Fibrillation Screening in High‐Risk Population: A Cross‐Sectional Study

open access: yesAGING MEDICINE, EarlyView.
Distribution of KAP scores for participants ≤ 65 versus > 65 years. ABSTRACT Objectives Atrial fibrillation (AF) is a common clinical arrhythmia. Failure to identify AF leaves patients at a considerably higher risk of disability and death, making its early screening and prevention extremely important. This study aimed to investigate knowledge, attitude,
Zhong Yi   +12 more
wiley   +1 more source

Potentially Inappropriate Medications and Drug–Drug Interactions in Geriatrics Cardiac Patients Visiting to Tertiary Care Central Hospital of Nepal

open access: yesAGING MEDICINE, EarlyView.
Elderly cardiac patients are usually taking multiple medications. These cause them to encounter potentially inappropriate medications and drug–drug interactions, which increase the risk of adverse health outcomes as well as the economic burden caused by them.
Roshan Giri   +5 more
wiley   +1 more source

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