Results 61 to 70 of about 421,250 (298)

NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2

Advanced Science, EarlyView.
The loss of NFS1 leads to its reduced binding with the transcription factor SP2, resulting in decreased expression of the downstream gene Idh2. This causes a shift in energy supply toward glycolysis in VSMCs, ultimately contributing to the occurrence and progression of AAA.
Luzheng Zhang, Yu Zhang, Dezhong Wen, Suxiang Guo, Xiaohui Qi, Heng Wang, Yujin Sun, Guangdong Yang, Yuehong Wang, Song Xue   +9 more
wiley   +1 more source

DEMOGRAPHICS AND CHARACTERISTICS OF CARDIOVASCULAR MEDICINE CHIEF FELLOWS IN THE UNITED STATES: INSIGHTS FROM THE AMERICAN COLLEGE OF CARDIOLOGY CARDIOVASCULAR MEDICINE CHIEF FELLOW NETWORK

Journal of the American College of Cardiology, 2020
Chief Fellows (CF) are vital members of cardiology training programs in the United States. Data regarding their experience, responsibilities, and skills are limited. In July 2019, the ACC Fellow in Training Section Leadership Council launched an affinity group for CF: the Cardiovascular Medicine ...
Nosheen Reza, Erik Frandsen, Sena Kilic, Ada Stefanescu Schmidt   +3 more
openaire   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Achievement of multiple therapeutic targets for cardiovascular disease prevention. Retrospective analysis of real practice in Italy [PDF]

, 2018
Background: Pharmacological therapy in patients at high cardiovascular (CV) risk should be tailored to achieve recommended therapeutic targets. Hypothesis: To evaluate individual global CV risk profile and to estimate the control rates of multiple ...
American Diabetes Association, Banegas, Bassand, Borghi, Conroy, Easton, Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults, Goldstein, Graham, Grundy, Grundy, Halcox, Kotseva, Mancia, Piepoli, Prugger, Rosengren, Rydén, Sakhuja, Sesti, Thygesen, Tocci, Tocci, Tocci, Tocci, Tocci, Tocci, Van de Werf, Volpe, Volpe, Volpe, Volpe, Whyte, Yusuf   +33 more
core   +1 more source

Bioabsorbable Endovascular Adhesive Tape (BEAT) for Improving Vascular Regeneration

Advanced Science, EarlyView.
A bioabsorbable endovascular adhesive tape (BEAT) platform based on a hierarchical polyelectrolyte complex is developed to enhance drug delivery in the DCB system. The coating enables rapid transfer to the vessel, provides short‐term mechanical support, and promotes both immediate transfer and long‐term retention of drugs at the lesion site.
Jiarong Wang, Jing Wang, Xinyi Li, Bo Yu, Yiduo Chen, Yirong Guo, Honglin Qian, Meng Hu, Haoyang Liu, Wenhui Liu, Han Xu, Kefeng Ren, M. Cristina L. Martins, Jian Ji   +13 more
wiley   +1 more source

[Bibliometric analysis of peruvian scientific production in cardiology and cardiovascular medicine].

Archivos peruanos de cardiologia y cirugia cardiovascular, 2021
Objetivo. Determinar las características y la tendencia de los artículos publicados sobre cardiología y medicina cardiovascular en el contexto peruano, y comprender cómo ha cambiado a lo largo de los años. Materiales y métodos. Se realizó un estudio bibliométrico de artículos originales publicados hasta el año 2020 por autores peruanos en revistas ...
Vargas-Fernández, Rodrigo, Visconti-Lopez, Fabriccio J., Barón-Lozada, Francisco A., Basualdo-Meléndez, Gianfranco W.   +3 more
openaire   +2 more sources

The future of cardiovascular imaging and non-invasive diagnosis☆A joint statement from the European Association of Echocardiography, the Working Groups on Cardiovascular Magnetic Resonance, Computers in Cardiology, and Nuclear Cardiology of the European Society of Cardiology, the European Association of Nuclear Medicine and the Association for European Paediatric Cardiology [PDF]

European Journal of Echocardiography, 2006
Advances in medical imaging now make it possible to investigate any patient with cardiovascular disease using multiple methods which vary widely in their technical requirements, benefits, limitations and costs. The appropriate use of alternative tests requires their integration into joint clinical diagnostic services where experts in all methods ...
Alan G, Fraser, Peter T, Buser, Jeroen J, Bax, Willem R, Dassen, Petros, Nihoyannopoulos, Jürg, Schwitter, Juhani M, Knuuti, Martin, Höher, Frank, Bengel, András, Szatmári   +9 more
openaire   +5 more sources

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source

Cardiac evaluation of young athletes: Time for a risk-based approach? [PDF]

, 2020
Pre-participation cardiovascular screening (PPCS) is recommended by several scientific and sporting organizations on the premise that early detection of cardiac disease provides a platform for individualized risk assessment and management; which has been
Drezner, JA, MacLachlan, H
core   +1 more source

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

Advanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen, Ioannis Ziogas, Shirina Alsaedi, Mouza Alshehhi, Shahd Almheiri, Adil Rehman, Khulood Al Shehhi, Hani Saleh, Ahsan Khandoker, Charalampos Pitsalidis, Antoun Khawaja, Anna‐Maria Pappa   +11 more
wiley   +1 more source