Results 71 to 80 of about 2,980,915 (356)
Towards Integrative Multi-Modal Personal Health Navigation Systems: Framework and Application [PDF]
arXiv, 2021 It is well understood that an individual's health trajectory is influenced by choices made in each moment, such as from lifestyle or medical decisions. With the advent of modern sensing technologies, individuals have more data and information about themselves than any other time in history.
arxiv
Development, validation, and implementation of biomarker testing in cardiovascular medicine state-of-the-art: proceedings of the European Society of Cardiology—Cardiovascular Round Table [PDF]
Cardiovascular Research, 2020 Abstract Many biomarkers that could be used to assess ejection fraction, heart failure, or myocardial infarction fail to translate into clinical practice because they lack essential performance characteristics or fail to meet regulatory standards for approval.
Christian W. Hamm +19 more
openaire +6 more sources
Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization
Advanced Science, EarlyView.This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao +15 more
wiley +1 more source
Peripartum Cardiomyopathy: Risks Diagnosis and Management
Journal of Multidisciplinary Healthcare, 2023 Selma Carlson,1,2 Jessica Schultz,1 Bhavadharini Ramu,3 Melinda B Davis4 1Division of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN, USA; 2Division of Cardiology, Minneapolis VA Medical Center, Minneapolis, MN, USA ...
Carlson S, Schultz J, Ramu B, Davis MB
doaj
Advanced Science, EarlyView.In intestinal epithelial cells, Gastrin/CCKBR stimulation prevents high glucose‐stimulated SGLT1 (SLC5A1) and GLUT2 (SLCA2) expressions, via the PI3K/AKT/eIF4B signaling pathway, with facilitatory effects on the secretion of incretins, which could be therapeutic targets for clinical treatment in T2D.
Xue Liu +13 more
wiley +1 more source
Vascular Health and Risk Management, 2020 Vladislav Zhitny,1 Noama Iftekhar,2 Luzviminda Alexander,1,3 Chowhdury Ahsan1,3 1School of Medicine, University of Nevada Las Vegas, Las Vegas, NV, USA; 2Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA; 3Department of Cardiology ...
Zhitny V +3 more
doaj
Joint Alignment of Multivariate Quasi-Periodic Functional Data Using Deep Learning [PDF]
arXiv, 2023 The joint alignment of multivariate functional data plays an important role in various fields such as signal processing, neuroscience and medicine, including the statistical analysis of data from wearable devices. Traditional methods often ignore the phase variability and instead focus on the variability in the observed amplitude.
arxiv
Metabolic Syndrome Derived from Principal Component Analysis and Incident Cardiovascular Events: The Multi Ethnic Study of Atherosclerosis (MESA) and Health, Aging, and Body Composition (Health ABC). [PDF]
, 2012 Background. The NCEP metabolic syndrome (MetS) is a combination of dichotomized interrelated risk factors from predominantly Caucasian populations. We propose a continuous MetS score based on principal component analysis (PCA) of the same risk factors in
Agarwal, Subhashish +14 more
core +4 more sources
Advanced Science, EarlyView.Low concentrations of lactate are transported to macrophages via MCT1, which upregulates the levels of histone H4K12la and promotes the transcription and secretion of TGF‐β in macrophages. TGF‐β subsequently enters fibroblasts through TGF‐β receptors, stimulating collagen synthesis.
Ying Zou +11 more
wiley +1 more source