Results 71 to 80 of about 413,528 (329)

The role of the emergency department in the management of acute heart failure: an international perspective on education and research [PDF]

, 2015
Emergency departments are a major entry point for the initial management of acute heart failure (AHF) patients throughout the world. The initial diagnosis, management and disposition - the decision to admit or discharge - of AHF patients in the emergency
Bueno, Hector, Collins, Sean P, DI SOMMA, Salvatore, Diercks, Deborah B, Gray, Alasdair, Harjola, Veli Pekka, Hollander, Judd E, Lambrinou, Ekaterini, Levy, Phillip D, Miró, Òscar, Möckel, Martin, Pang, Peter S, Papa, Annmarie   +12 more
core   +1 more source

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

Advanced Science, EarlyView.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao, Huailong An, Cong Fan, Qingsu Lan, Hongyu Zhong, Yun Zhang, Libo Zhou, Panpan Hao   +7 more
wiley   +1 more source

HMGB2 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through MTA2‐Driven Metabolic Reprogramming

Advanced Science, EarlyView.
In contrast to the adult mammalian heart, which lacks regenerative capacity, the neonatal heart retains a transient regenerative capacity. In this study, high mobility group box 2 (HMGB2) is identified as a crucial protein driving heart regeneration based on comprehensive analyses using quantitative proteomics with tandem mass tag (TMT) labelling, RNA ...
Liu‐Hua Zhou, Ling‐Feng Gu, Yi‐Xi Chen, Peng Jing, Tong‐Tong Yang, Ye He, Yu‐Lin Bao, Xiang‐Zheng Zhang, Chong Du, Si‐Bo Wang, Tian‐Kai Shan, Jia‐Yi Chen, Hao Wang, Qi‐Ming Wang, Li‐Ping Xie, Yang Zhao, Yong Ji, Lian‐Sheng Wang   +17 more
wiley   +1 more source

Cystatin C as a Predictor of Major Adverse Cardiovascular Event in Patients with Acute Myocardial Infarction Without Cardiogenic Shock and Renal Impairment After Coronary Intervention

International Journal of General Medicine, 2023
Trisulo Wasyanto,1 Ahmad Yasa,1 Yoga Yudhistira2 1Department of Cardiology and Vascular Medicine, Faculty of Medicine, Sebelas Maret University/Dr. Moewardi Hospital, Surakarta, Indonesia; 2Department of Cardiology and Vascular Medicine, Faculty of ...
Wasyanto T, Yasa A, Yudhistira Y
doaj  

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

Advanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma, Zhenbo Han, Jooman Park, Gege Yan, Sen Zhang, Youjeong Kwon, Sarath Babu Nukala, Jindpreet Kandola, Sandra Pinho, Chong Wee Liew, Yuwei Jiang, Sang‐Ging Ong   +11 more
wiley   +1 more source

Coronary CT Angiography and 5-Year Risk of Myocardial Infarction. [PDF]

, 2018
BACKGROUND: Although coronary computed tomographic angiography (CTA) improves diagnostic certainty in the assessment of patients with stable chest pain, its effect on 5-year clinical outcomes is unknown.
Adamson, Philip D., Berry, Colin, Boon, Nicholas A., Boylan, Heather, Brown, Ammani, Connolly, Eugene, Dweck, Marc R., Farrell, Lesley, Flather, Marcus, Forbes, John, Frood, Alison, Glover, Caroline, Hunter, Amanda, Johnstone, Janet, Lanaghan, Kirsten, Lewis, Stephanie, MacLean, Scott, Mangion, Kenneth, McGlynn, Deborah, McGregor, Lorraine, McLennan, Evonne, Mills, Nicholas L., Mordi, Ify, Murdoch, Laura, Newby, David E., Norrie, John, Paterson, Victoria, Roditi, Giles, Shah, Anoop S.V., Steedman, Tracey, Teenan, Marion, Teyhan, Fiona, The SCOT-HEART Investigators,, Timmis, Adam D., Tzemos, Nikolaos, van Beek, Edwin J.R., Williams, Michelle C., Woodward, Rosie   +37 more
core   +6 more sources

Prognostic value of the myocardial salvage index measured by T2-weighted and T1-weighted late gadolinium enhancement magnetic resonance imaging after ST-segment elevation myocardial infarction: A systematic review and meta-regression analysis [PDF]

, 2020
In all patients with ST-segment elevation myocardial infarction, risk stratification should be performed before discharge. The measurement of therapy efficiency with magnetic resonance imaging has been proposed as part of the risk assessment, but it has ...
Dewey, Marc, Kendziora, Benjamin
core   +1 more source

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Advanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu, Min Chen, Chen‐Yu Jiang, Dai‐Ji Jiang, Xu Zhang, Xiao‐He Xu, Yi‐Wei Liu, Bei Feng, Lin‐Cai Ye, Yang‐Yang He, Xu Huang, Yi‐Chi Zhang, Xing‐Liang Zhou, Yi Shen, Tian‐Yu Liu, Li‐Jun Fu, Yi Yan, Hao Zhang   +17 more
wiley   +1 more source

A Heart-Healthy Diet for Cardiovascular Disease Prevention: Where Are We Now?

Vascular Health and Risk Management, 2023
Alaa Diab,1,2 L Nedda Dastmalchi,3 Martha Gulati,4 Erin D Michos1,5 1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; 2Department of Medicine, Greater Baltimore Medical Center, Baltimore, MD, USA; 3Division
Diab A, Dastmalchi LN, Gulati M, Michos ED   +3 more
doaj  

Seipin‐Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu, Junxia Zhang, Yusi Chen, Geng Shen, Yufei Han, Zihao Zhou, Jinxuan Chen, Xuya Kang, Huilin Qu, Jiaxin Duanmu, Haibao Shang, Yingjia Li, Wei Huang, Yan Zhang   +13 more
wiley   +1 more source