Results 141 to 150 of about 61,574 (301)
British Journal of Clinical Pharmacology, EarlyView.Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga +20 more
wiley +1 more source
Computational Cardiology — A New Discipline of Translational Research
Genomics, Proteomics & Bioinformatics, 2016 Benjamin Meder +2 more
doaj +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Coronary artery disease (CAD) with severe calcification remains a growing challenge in percutaneous coronary intervention (PCI). Atherectomy (ATH) has long been used for plaque modification, whereas intravascular lithotripsy (IVL) has emerged as a promising alternative. Large‐scale comparative data on long‐term outcomes are limited.
Charles D. Miks +3 more
wiley +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Advanced heart failure (HF) remains a clinical challenge, and mitral transcatheter edge‐to‐edge repair (M‐TEER) has emerged as a potential bridging strategy. Aims To describe the clinical outcomes of M‐TEER in a single‐center cohort of patients with advanced HF and to identify anatomical and clinical features potentially associated ...
Pedro Castilhos de Freitas Crivelaro +8 more
wiley +1 more source
Herz, 2006 The group of restrictive cardiomyopathies (RKMP) includes a number of myocardial and endomyocardial diseases. These entities are characterized by stiffening of both ventricles resulting in a deterioration of ventricular filling and severe diastolic dysfunction. Systolic ventricular function is usually normal or only mildly impaired.
Wachter, R. Rolf, Pieske, Burkert M.
openaire +2 more sources
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Development of conduction abnormalities requiring pacing after transcatheter aortic valve replacement (TAVR) is relatively common. The effects of post‐TAVR permanent pacemaker (PPM) implantation on mortality, ischemic stroke, and cardiovascular outcomes remain incompletely characterized.
Omar Saleh +7 more
wiley +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT This patient is a 77‐year‐old male with non‐ischemic cardiomyopathy, severe tricuspid regurgitation, and moderate mitral regurgitation who underwent simultaneous transcatheter edge‐to‐edge repair of both mitral and tricuspid valves. Post‐procedure, the patient exhibited significant symptomatic improvement and reduced regurgitation severity ...
Omar Khan, Matthew Summers
wiley +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Atrial fibrillation (AF) is a frequent comorbidity in patients with severe aortic valve stenosis undergoing transcatheter aortic valve implantation (TAVI). In addition, new‐onset AF can occur after TAVI. However, data on how AF affects outcomes in patients undergoing TAVI remain conflicting.
Kimberley I. Hemelrijk +23 more
wiley +1 more source
Chronic Diseases and Translational Medicine, EarlyView.Endogenous GLP‐1 and exogenous GLP‐1 RAs activate GLP‐1R‐expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic circuits that regulate metabolic homeostasis. Hypothalamic efferent vagal output to the liver suppresses lipogenesis, enhances triglyceride export, and ...
Gabriel Amorim Moreira Alves +8 more
wiley +1 more source