Results 191 to 200 of about 296,757 (381)
Hide and Seek: Protein-coding Sequences Inside “Non-coding” RNAs
Genomics, Proteomics & Bioinformatics, 2016 Daniel Oehler, Jan Haas
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Heart transplantation (HT) is frequently complicated by chronic kidney disease, of which tacrolimus‐related nephrotoxicity is an important cause. In kidney and liver transplant recipients, fast tacrolimus metabolism (defined as a low concentration‐to‐dose [C0/D] ratio), negatively affects kidney function.
Maaike R. Schagen +9 more
wiley +1 more source
Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload. [PDF]
, 2018 The integration of in vitro cardiac tissue models, human induced pluripotent stem cells (hiPSCs) and genome-editing tools allows for the enhanced interrogation of physiological phenotypes and recapitulation of disease pathologies.
Boggess, Steven +8 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims Observational studies have suggested associations between heart failure (HF), frailty and poisoning by narcotics and psychodysleptics (PNP). However, establishing causal relationships has been challenging. This study used a two‐sample Mendelian randomization (MR) approach to investigate the genetically proxied causality between HF ...
Bing Wang +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Several methods exist to identify hospital admissions related to adverse drug events (ADEs). Clinical adjudication by healthcare professionals is the gold standard but is labour‐intensive. Spontaneous reporting and routinely collected healthcare data using a set of International Classification of Diseases (ICD) codes often underestimate the ...
Zuzana Juhásová +2 more
wiley +1 more source