Results 221 to 230 of about 127,271 (293)

Yield of Genetic Testing in Pediatric Cardiomyopathies: Implications for Novel Therapeutic Options. [PDF]

Mol Genet Genomic Med
Ballerini A, Girolami F, Gozzini A, Passantino S, Zampieri M, Marchi A, Tomberli A, Calabri GB, Spaziani G, Porcedda G, Bennati E, Favilli S, Olivotto I.   +12 more
europepmc   +1 more source

Atrial cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala, Monika Przewłocka‐Kosmala   +1 more
wiley   +1 more source

Convergent evolution of metabolic functions: Evidence from the gut microbiomes of humans and dogs

iMetaOmics, EarlyView.
Dogs have undergone convergent evolution in their genome with humans in long‐term co‐living. Studies have shown that the gut microbiomes of dogs exhibit greater similarity to those of humans compared to mice and pigs. In our study, we first compared the gut microbiomes of macaques, three dog groups, and two wolf groups to those in humans.
Xiaoyang Wang, Lei Zhu, Yue Lan, Guimei Li, Tong Zhou, Qingguo Huang, Tifei Yuan, Chen Tian, Zhenxin Fan, Zhigang Zhang, Guo‐Dong Wang   +10 more
wiley   +1 more source

Spectrum and Clinical Interpretation of <i>TTN</i> Variants in Ecuadorian Patients with Heart Disease: Insights into VUS and Likely Pathogenic Variants. [PDF]

Int J Mol Sci
Guevara-Ramírez P, Cadena-Ullauri S, Tamayo-Trujillo R, Ruiz-Pozo VA, Paz-Cruz E, Ibarra-Castillo R, Laso-Bayas JL, Zambrano AK.   +7 more
europepmc   +1 more source

Exploring the Link Between Psoriasis and Genetic Predictors of Cardiac Magnetic Resonance Traits: A Bidirectional Mendelian Randomization Study

iNew Medicine, EarlyView.
ABSTRACT Psoriasis is a chronic autoimmune disease characterized by systemic inflammation and skin involvement, affecting millions of individuals worldwide. However, few studies have evaluated whether psoriasis and cardiac magnetic resonance imaging (CMR) traits share a common genetic basis.
Junlin Yang, Pengzhan Yin, Shutian An, Zhanglei Li, Yewen Jiang, Jun Wang, Yongqiang Yu, Ren Zhao, Xiaohu Li   +8 more
wiley   +1 more source

From Rare Genetic Variants to Polygenic Risk: Understanding the Genetic Basis of Cardiomyopathies. [PDF]

J Cardiovasc Dev Dis
Garcia-Ruano AB, Sola-Garcia E, Martin-Istillarty M, Urbano-Moral JA.   +3 more
europepmc   +1 more source

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

Interdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen, Qiuhan Wang, Mengjia Shen, Mingjue Li, Yingqi Zhu, Cankun Zheng, Siyuan Ma, Hairuo Lin, Xiaokang Fu, Rui Zhang, Jianping Bin, Yulin Liao, Qiancheng Wang   +12 more
wiley   +1 more source

GSDME in cardiovascular diseases: research system and contemporary progress. [PDF]

Front Immunol
Yang Z, Luo Z, Zhang H, Zong J, Huang P, Niu Y, Zhou C, Wang S, Zhang D.   +8 more
europepmc   +1 more source

Model Informed Precision Dosing of Tacrolimus in Children Following Heart Transplant

The Journal of Clinical Pharmacology, EarlyView.
Abstract Tacrolimus is a first‐line immunosuppressant used after solid organ transplantation that suffers from extensive intra‐ and inter‐patient variability and a narrow therapeutic window. Its critical role in a fragile population, coupled with the difficulties identifying and maintaining an appropriate dose within a given patient, make it an ideal ...
Jadon S. Wagstaff, Shaun S. Kumar, Kimberly M. Molina, Joseph E. Rower   +3 more
wiley   +1 more source

Echocardiographic Features of Cardiomyopathies: A Comprehensive Review. [PDF]

Echocardiography
Al-Naami GH.
europepmc   +1 more source