Results 321 to 330 of about 296,757 (381)

Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad   +9 more
wiley   +1 more source

The contemporary role of genetics in cardiovascular medicine: from phenotypes to precision diagnoses. [PDF]

open access: yesEur Heart J Suppl
Urtis M   +9 more
europepmc   +1 more source

Electron microscopic findings predict clinical outcomes in patients with non‐ischaemic cardiomyopathy

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Electron microscopy reveals microstructural alterations in cardiomyocyte nuclei and myofilaments in non‐ischaemic cardiomyopathy (NICM), particularly in dilated cardiomyopathy (DCM). Nevertheless, the correlation between such observations and clinical outcomes, including prognosis and left ventricular reverse remodelling (LVRR), remains ...
Rie Higuchi   +19 more
wiley   +1 more source

The Future of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 Gene Therapy in Cardiomyopathies: A Review of Its Therapeutic Potential and Emerging Applications. [PDF]

open access: yesCureus
Moradi A   +11 more
europepmc   +1 more source

Transthyretin amyloid cardiomyopathy in aortic stenosis patients scheduled for transcatheter aortic valve implantation

open access: yesESC Heart Failure, EarlyView.
Abbreviations: TAVI, transcatheter aortic valve implantation; ATTR‐CM, transthyretin cardiac amyloidosis. We aimed to diagnose occult ATTR‐CM in patients with severe aortic stenosis undergoing TAVI using bone scintigraphy. We verified a diagnosis of ATTR‐CM in 8 of 171 (4.7 %) consecutive aortic stenosis patients who underwent TAVI.
Margrethe Flesvig Holt   +15 more
wiley   +1 more source

When the conduction disturbance expresses a cardiomyopathy. [PDF]

open access: yesEur Heart J Suppl
Calò L   +18 more
europepmc   +1 more source

Discovering new hub genes of dilated cardiomyopathy

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified. The present study aimed to explore new hub genes of DCM by mining the human DCM databases and further by experimental validation.
Jun‐Yan Zhu   +9 more
wiley   +1 more source

Microaxial pump‐supported coronary surgery without CPB to optimize outcome in severely impaired left ventricles

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Cardiopulmonary bypass (CPB) is the standard approach for coronary artery bypass grafting (CABG) in advanced ischaemic cardiomyopathy. Microaxial pump support has been envisioned to allow for beating‐heart CABG without CPB (MPCAB), thereby avoiding CPB‐inherent complications.
Anna Kathrin Assmann   +5 more
wiley   +1 more source

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