Results 101 to 110 of about 126,108 (297)
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler +4 more
wiley +1 more source
The aim. was to study peculiarities of ischemic and idiopathic dilated cardiomyopathy and. aggregative activity of thrombocytes and. also the response to the therapy by beta-blockers (Atenolol and Bisoprolol). Material and.
P. N. Isakhanova, Yu. N. Ziyaev
doaj
Cardiovascular Immunology Research in Wuhan Union Hospital: Over the Past 25 years
Cardiovascular immunology research in Wuhan Union Hospital began in 1991. Anti-heart antibodies in dilated cardiomyopathy and acute viral myocarditis began to be reported from 1993.
Yuhua Liao, Yiyi Wang
doaj +1 more source
We propose a joint model for a time-to-event outcome and a quantile of a continuous response repeatedly measured over time. The quantile and survival processes are associated via shared latent and manifest variables.
Aalen +56 more
core +1 more source
Increased COUP-TFII expression in adult hearts induces mitochondrial dysfunction resulting in heart failure [PDF]
Mitochondrial dysfunction and metabolic remodelling are pivotal in the development of cardiomyopathy. Here, we show that myocardial COUP-TFII overexpression causes heart failure in mice, suggesting a causal effect of elevated COUP-TFII levels on ...
Bellen, Hugo J. +13 more
core +1 more source
Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo +7 more
wiley +1 more source
Evidence regarding clinical use of microvolt T-wave alternans [Accuracy of microvolt T-wave alternans testing] [PDF]
Background: Microvolt T-wave alternans (MTWA) testing in many studies has proven to be a highly accurate predictor of ventricular tachyarrhythmic events (VTEs) in patients with risk factors for sudden cardiac death (SCD) but without a prior history of ...
Cohen, Richard J. +2 more
core
Dilated cardiomyopathy in children
Dilated cardiomyopathy is a rare but serious disease in children. Clinical manifestations are primarily due to impaired systolic function of the left ventricle. Diagnostic evaluation is important to exclude masquerading cardiac abnormalities and to assess the degree of myocardial dysfunction.
openaire +2 more sources
The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley +1 more source
Dilated cardiomyopathy (DCM) is a heart disease that enlarges the heart muscle and reduces its function, leading to heart failure, arrhythmia, and sudden cardiac death. The causes of DCM are not always clear, but may include genetic mutations, viral infections, alcohol abuse, and certain medications. Common symptoms include shortness of breath, fatigue,
openaire +3 more sources

