Results 101 to 110 of about 126,108 (297)

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

EFFECT OF BETA-BLOCKERS AND STUDY OF AGGREGATiVE ACTIVITY OF THROMBOCYTES IN PATiENTS WITH DILATED CARDIOMYOPATHY

open access: yesActa Biomedica Scientifica, 2012
The aim. was to study peculiarities of ischemic and idiopathic dilated cardiomyopathy and. aggregative activity of thrombocytes and. also the response to the therapy by beta-blockers (Atenolol and Bisoprolol). Material and.
P. N. Isakhanova, Yu. N. Ziyaev
doaj  

Cardiovascular Immunology Research in Wuhan Union Hospital: Over the Past 25 years

open access: yesCardiovascular Innovations and Applications, 2017
Cardiovascular immunology research in Wuhan Union Hospital began in 1991. Anti-heart antibodies in dilated cardiomyopathy and acute viral myocarditis began to be reported from 1993.
Yuhua Liao, Yiyi Wang
doaj   +1 more source

Longitudinal quantile regression in presence of informative drop-out through longitudinal-survival joint modeling

open access: yes, 2014
We propose a joint model for a time-to-event outcome and a quantile of a continuous response repeatedly measured over time. The quantile and survival processes are associated via shared latent and manifest variables.
Aalen   +56 more
core   +1 more source

Increased COUP-TFII expression in adult hearts induces mitochondrial dysfunction resulting in heart failure [PDF]

open access: yes, 2015
Mitochondrial dysfunction and metabolic remodelling are pivotal in the development of cardiomyopathy. Here, we show that myocardial COUP-TFII overexpression causes heart failure in mice, suggesting a causal effect of elevated COUP-TFII levels on ...
Bellen, Hugo J.   +13 more
core   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo   +7 more
wiley   +1 more source

Evidence regarding clinical use of microvolt T-wave alternans [Accuracy of microvolt T-wave alternans testing] [PDF]

open access: yes, 2011
Background: Microvolt T-wave alternans (MTWA) testing in many studies has proven to be a highly accurate predictor of ventricular tachyarrhythmic events (VTEs) in patients with risk factors for sudden cardiac death (SCD) but without a prior history of ...
Cohen, Richard J.   +2 more
core  

Dilated cardiomyopathy in children

open access: yesJournal of the American College of Cardiology, 1988
Dilated cardiomyopathy is a rare but serious disease in children. Clinical manifestations are primarily due to impaired systolic function of the left ventricle. Diagnostic evaluation is important to exclude masquerading cardiac abnormalities and to assess the degree of myocardial dysfunction.
openaire   +2 more sources

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

Dilated cardiomyopathy

open access: yes, 2023
Dilated cardiomyopathy (DCM) is a heart disease that enlarges the heart muscle and reduces its function, leading to heart failure, arrhythmia, and sudden cardiac death. The causes of DCM are not always clear, but may include genetic mutations, viral infections, alcohol abuse, and certain medications. Common symptoms include shortness of breath, fatigue,
openaire   +3 more sources

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