Results 121 to 130 of about 117,203 (208)

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

Natural products targeting regulated cell deaths for adriamycin-induced cardiotoxicity

Cell Death Discovery
Adriamycin (ADR), as an anti-cancer drug in routine clinical application, is utilized to treat various cancers such as ovarian cancer, hematological malignant tumor, and endometrial carcinoma.
Zheng Wang, Yanli Zhu, Yu Yao, Wenyu Zhang, Bo Wang, Jing Wang, Yang Yang, Liwen Liu   +7 more
doaj   +1 more source

Safety and Utility of Smartphone‐Based Heart Monitors in Pediatric Patients With Cardiovascular Implantable Electronic Devices

Journal of Cardiovascular Electrophysiology, EarlyView.
Smartphone heart monitors in pediatric CIEDs: A pilot study. Smartphone heart monitors did not induce EMI in children with CIEDs, enabling reliable heart rate measurement and accurate identification of ventricular non‐captures. ABSTRACT Background Portable heart monitors enable on‐demand electrocardiogram (ECG) recordings and enhance symptom‐rhythm ...
Chun‐Lok Ho, Sit‐Yee Kwok, Sabrina S. L. Tsao, Yiu‐Fai Cheung   +3 more
wiley   +1 more source

Clinical Outcomes After Catheter Ablation in Patients With Structural Heart Disease and Ventricular Fibrillation

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction In patients with ischemic cardiomyopathy (ICM), recurrent VF may be treated with catheter ablation by targeting triggering premature ventricular complexes (PVCs) and/or ventricular scar homogenization. Data on optimal ablation strategies in patients with non‐ischemic cardiomyopathy (NICM) remain limited.
Kenji Hashimoto, Samual Turnbull, Saurabh Kumar   +2 more
wiley   +1 more source

The First Report of Cod Gill Poxvirus in Gills of Atlantic Cod (Gadus morhua L.) Suffering From Cardiorespiratory Disease

Journal of Fish Diseases, Volume 48, Issue 4, April 2025.
ABSTRACT Atlantic cod farming experiences renewed growth in Norway, and increased awareness is essential to address emerging diseases in this species. There are few reports on gill diseases in cod, and to date, no viral gill infections of cod have been documented. In this study, we collected samples from three sequential time points in summer 2023 from
Mona C. Gjessing, Torstein Tengs, Hanne Nilsen, Saima Mohammad, Simon C. Weli   +4 more
wiley   +1 more source

Autosomal recessive dilated cardiomyopathy due to DOLK mutations results from abnormal dystroglycan O-mannosylation [PDF]

, 2011
Genetic causes for autosomal recessive forms of dilated cardiomyopathy (DCM) are only rarely identified, although they are thought to contribute considerably to sudden cardiac death and heart failure, especially in young children.
Steenbergen, Gerry, van Reeuwijk, Jeroen, Lefeber, Dirk J, Kapusta, Livia, Wevers, Ron A, Zucker, Nili, Lammens, Martin, Absmanner, Birgit, Morava, Eva, van den Akker, Willem M R, Knopf, Carlos, Verrijp, Kiek, Grunewald, Stephanie, Schuurs-Hoeijmakers, Janneke H M, van Bokhoven, Hans, Jóźwiak, Adam, Lorber, Avraham, Riemersma, Moniek, Huijben, Karin, Lehle, Ludwig, Mandel, Hanna   +20 more
core  

Expanding the Clinical Spectrum of DHX30‐Related Neurodevelopmental Disorder: A Case Report and a Scoping Review

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Whole exome sequencing (WES) has improved diagnostic rates for neurodevelopmental disorders (NDDs) while introducing challenges in novel variant interpretation. DHX30‐related NDD (DHX30‐NDD) is a recently described condition with an evolving phenotypic spectrum.
Nattaporn Tassanakijpanich, Areerat Hnoonual, Oradawan Plong‐On, Pornprot Limprasert   +3 more
wiley   +1 more source

First Experience With Extravascular Implantable Cardioverter‐Defibrillator Under Deep Sedation

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background The Extravascular Implantable Cardioverter‐Defibrillator (EV‐ICD) utilizes a substernal lead to provide defibrillation and anti‐tachycardia pacing (ATP) while avoiding transvenous complications. General anesthesia (GA) was applied for implantation procedures in the EV‐ICD pivotal trial and is currently recommended by the ...
Nibras Soubh, Bernhard C. Danner, Ulrich Krause, Matthias J. Müller, Markus Zabel, Gerd Hasenfuß, Constanze Schmidt, Helge Haarmann, Eva Rasenack, Leonard Bergau   +9 more
wiley   +1 more source

On-pump intracardiac echocardiography during septal myectomy for hypertrophic cardiomyopathyCentral Message

JTCVS Techniques, 2020
David M. Williams, MD, Robert G. Nampi, MD, Muhamed Saric, MD, PhD, Eugene A. Grossi, MD, Mark V. Sherrid, MD, Daniel G. Swistel, MD   +5 more
doaj   +1 more source

Rising Comorbidity Burden in Inpatient Atrial Fibrillation Catheter Ablation: Temporal Trends and In‐Hospital Outcomes

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Despite advancements in catheter ablation (CA) technique and expertise, success rates of atrial fibrillation (AF) ablation have not substantially improved in recent years. Treating patients with advanced age and higher comorbidities may limit success rates while increasing complications.
Eran Leshem, Bar Ehrenberg, Adam Folman, Mark Kazatsker, Ariel Roguin, Gilad Margolis   +5 more
wiley   +1 more source