Results 101 to 110 of about 413,499 (385)

Association between serum cystatin C and early impairment of cardiac function and structure in type 2 diabetes patients with normal renal function

Clinical Cardiology, Volume 45, Issue 12, Page 1287-1296, December 2022., 2022
Abstract Background Type 2 diabetes mellitus (T2DM) patients may have cardiac remodeling and dysfunction from the early stage of disease. This study aimed to determine the association between cystatin C (CysC) and early cardiac functional or structural impairment in T2DM patients without renal dysfunction.
Zhuoshan Huang, Junlin Zhong, Shaozhao Zhang, Zhenyu Xiong, Yiquan Huang, Menghui Liu, Yifen Lin, Xiangbin Zhong, Xiaomin Ye, Xiaodong Zhuang, Xinxue Liao   +10 more
wiley   +1 more source

A Novel Protein NAB1‐356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis

Advanced Science, EarlyView.
The circRNA circNAB1 is downregulated in AF patient. Silencing circNAB1 promotes collagen deposition and inflammation, whereas overexpression reduces AF susceptibility. circNAB1 encodes the protein NAB1 356 that interacts with EGR1 to mitigate fibrosis and inflammation.
William W Du, Muhammad Rafiq, Hui Yuan, Xiangmin Li, Sheng Wang, Jun Wu, Jinfeng Wei, Ren‐Ke Li, Huiming Guo, Burton B Yang   +9 more
wiley   +1 more source

Prognostic value of global longitudinal strain in hypertrophic cardiomyopathy: A systematic review and meta‐analysis

Clinical Cardiology, Volume 45, Issue 12, Page 1184-1191, December 2022., 2022
Abstract Background As previously reported, impairment of left ventricular global longitudinal strain (LVGLS) is associated with myocardial fibrosis, arrhythmias, and heart failure in hypertrophic cardiomyopathy (HCM) patients. Hypothesis This study aimed to estimate the association between LVGLS measured by echocardiography and major adverse ...
Ying Yang, Dong Wu, Hui Wang, Yanting Wang   +3 more
wiley   +1 more source

Echocardiography-guided percutaneous intramyocardial alginate hydrogel implants for heart failure: canine models with 6-month outcomes

Frontiers in Cardiovascular Medicine
BackgroundEchocardiography-guided percutaneous intramyocardial alginate-hydrogel implantation (PIMAHI) is a novel treatment approach for heart failure (HF).
Hui Ma, Wenqing Gong, D. Scott Lim, Jing Li, Shengjun Ta, Rui Hu, Xiaojuan Li, Minjuan Zheng, Liwen Liu   +8 more
doaj   +1 more source

Dilated Cardiomyopathy: Genetic Determinants and Mechanisms

Circulation Research, 2017
Nonischemic dilated cardiomyopathy (DCM) often has a genetic pathogenesis. Because of the large number of genes and alleles attributed to DCM, comprehensive genetic testing encompasses ever-increasing gene panels.
E. McNally, L. Mestroni
semanticscholar   +1 more source

P21‐Activated Kinase 2 as a Novel Target for Ventricular Tachyarrhythmias Associated with Cardiac Adrenergic Stress and Hypertrophy

Advanced Science, EarlyView.
Ca2+/calmodulin‐dependent kinase II (CaMKII) activation is likely driven by oxidative stress, particularly excessive reactive oxygen species (ROS) production. This study identifies P21‐activated kinase 2 (Pak2) as a novel regulator of ROS‐induced CaMKII activation and abnormal Ca2⁺ dynamics in acute adrenergic and chronic pressure‐overload stressed ...
Tao Li, Ting Liu, Yan Wang, Yangpeng Li, Leiying Liu, James Bae, Yu He, Xian Luo, Zhu Liu, Tangting Chen, Xianhong Ou, Dan Zhang, Huan Lan, Juyi Wan, Yan Wei, Fang Zhao, Xin Wang, Tao Li, Christopher L.‐H. Huang, Chunxiang Zhang, Ming Lei, Xiaoqiu Tan   +21 more
wiley   +1 more source

Reversible Cardiomyopathies

Clinical Medicine Insights: Cardiology, 2015
Cardiomyopathies (CMs) have many etiological factors that can result in severe structural and functional dysregulation. Fortunately, there are several potentially reversible CMs that are known to improve when the root etiological factor is addressed. In this article, we discuss several of these reversible CMs, including tachycardia-induced, peripartum,
Harsh Patel, Raef Madanieh, Constantine E. Kosmas, Satya K. Vatti, Timothy J. Vittorio   +4 more
openaire   +4 more sources

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

Advanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong, Pei Li, Yi Jiang, Zhihan Wang, Shihui Fu, Hebin Che, Meng Liu, Xiaojing Zhao, Chunlei Liu, Chenghui Zhao, Qin Zhong, Chongyou Rao, Siwei Wang, Suyuan Liu, Dayu Hu, Dongjin Wang, Juntao Gao, Kai Guo, Xinwang Liu, En Zhu, Kunlun He   +20 more
wiley   +1 more source

Predictive value of estimated plasma volume for postoperative hypotension in percutaneous intramyocardial septal radiofrequency ablation treating for hypertrophic obstructive cardiomyopathy

BMC Cardiovascular Disorders
Background Estimated plasma volume status (ePVS) estimated by the Duarte formula is associated with clinical outcomes in patients with heart failure.
Bo Shan, Jing Li, Zhangwei Shi, Chao Han, Juan Zhang, Jia Zhao, Rui Hu, Liwen Liu, Shengjun Ta   +8 more
doaj   +1 more source

Self-attention based BiLSTM-CNN classifier for the prediction of ischemic and non-ischemic cardiomyopathy [PDF]

arXiv, 2019
Heart Failure is a major component of healthcare expenditure and a leading cause of mortality worldwide. Despite higher inter-rater variability, endomyocardial biopsy (EMB) is still regarded as the standard technique, used to identify the cause (e.g.
arxiv