Results 11 to 20 of about 441,361 (298)

Arrhythmogenic Cardiomyopathy.

Circulation Research, 2021
Arrhythmogenic cardiomyopathy is an inherited heart muscle disorder, predisposing to sudden cardiac death, particularly in young patients and athletes.
D. Corrado, C. Basso, D. Judge
semanticscholar   +1 more source

Endothelial Dysfunction and Diabetic Cardiomyopathy

Frontiers in Endocrinology, 2022
The cardiovascular complications contribute to a majority of diabetes associated morbidity and mortality, accounting for 44% of death in those patients with type 1 diabetes mellitus (DM) and 52% of deaths in type 2 DM.
Moran Wang, Yongsheng Li, Sheng Li, Jiagao Lv   +3 more
semanticscholar   +1 more source

Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications

Physiological Reviews, 2021
The prevalence of heart failure is on the rise and imposes a major health threat, in part, due to the rapidly increased prevalence of overweight and obesity.
Jun Ren, N. Wu, Shuyi Wang, J. Sowers, Yingmei Zhang   +4 more
semanticscholar   +1 more source

Myocarditis and inflammatory cardiomyopathy: current evidence and future directions

Nature Reviews Cardiology, 2020
Inflammatory cardiomyopathy, characterized by inflammatory cell infiltration into the myocardium and a high risk of deteriorating cardiac function, has a heterogeneous aetiology.
C. Tschöpe, E. Ammirati, B. Bozkurt, A. Caforio, L. Cooper, S. Felix, J. Hare, Bettina Heidecker, S. Heymans, N. Hübner, S. Kelle, K. Klingel, H. Maatz, A. Parwani, F. Spillmann, R. Starling, H. Tsutsui, P. Seferovic, S. Van Linthout   +18 more
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Ferroptosis as a target for protection against cardiomyopathy

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Nonapoptotic cell death-induced tissue damage has been implicated in a variety of diseases, including neurodegenerative disorder, inflammation, and stroke.
X. Fang, Hao Wang, Dan Han, Enjun Xie, Xiang Yang, Jiayu Wei, Shanshan Gu, F. Gao, N. Zhu, Xiangju Yin, Qi Cheng, Pan Zhang, Wei Dai, Jinghai Chen, Fuquan Yang, Huang-Tian Yang, A. Linkermann, W. Gu, J. Min, Fudi Wang   +19 more
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Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy

New England Journal of Medicine, 2018
Background Transthyretin amyloid cardiomyopathy is caused by the deposition of transthyretin amyloid fibrils in the myocardium. The deposition occurs when wild‐type or variant transthyretin becomes unstable and misfolds. Tafamidis binds to transthyretin,
M. Maurer, J. Schwartz, B. Gundapaneni, P. Elliott, G. Merlini, M. Waddington-Cruz, A. Kristen, M. Grogan, R. Witteles, T. Damy, B. Drachman, Sanjiv J. Shah, M. Hanna, D. Judge, A. Barsdorf, P. Huber, T. Patterson, S. Riley, J. Schumacher, M. Stewart, M. Sultan, C. Rapezzi   +21 more
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Incremental Prognostic Utility of Left Ventricular Global Longitudinal Strain in Hypertrophic Obstructive Cardiomyopathy Patients and Preserved Left Ventricular Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundIn obstructive hypertrophic cardiomyopathy patients with preserved left ventricular (LV) ejection fraction, we sought to determine whether LV global longitudinal strain (LV‐GLS) provided incremental prognostic utility.
Albree Tower‐Rader, Jorge Betancor, Zoran B. Popovic, Kimi Sato, Maran Thamilarasan, Nicholas G. Smedira, Harry M. Lever, Milind Y. Desai   +7 more
doaj   +1 more source

Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis

Circulation Research, 2020
Supplemental Digital Content is available in the text. Rationale: Maintaining iron homeostasis is essential for proper cardiac function. Both iron deficiency and iron overload are associated with cardiomyopathy and heart failure via complex mechanisms ...
X. Fang, Zhaoxian Cai, Hao Wang, Dan Han, Qi Cheng, Pan Zhang, F. Gao, Yingying Yu, Zijun Song, Qian Wu, P. An, Sicong Huang, Jianwei Pan, Houzao Chen, Jinghai Chen, A. Linkermann, J. Min, Fudi Wang   +17 more
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Septic Cardiomyopathy: From Pathophysiology to the Clinical Setting

Cells, 2022
The onset of cardiomyopathy is a common feature in sepsis, with relevant effects on its pathophysiology and clinical care. Septic cardiomyopathy is characterized by reduced left ventricular (LV) contractility eventually associated with LV dilatation with
F. Carbone, L. Liberale, A. Preda, T. Schindler, F. Montecucco   +4 more
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Trans-Septal Myocardial Biopsy in Hypertrophic Cardiomyopathy Using the Liwen Procedure: An Introduction of a Novel Technique

Journal of Interventional Cardiology, 2021
Objective. The purpose of this study was to evaluate the feasibility and safety of myocardial biopsy using a new approach, the Liwen procedure. Background.
Chao Han, Mengyao Zhou, Rui Hu, Bo Wang, Lei Zuo, Jing Li, Shengjun Ta, David H. Hsi, Jiani Liu, Lichun Wei, Liwen Liu   +10 more
doaj   +1 more source