Results 21 to 30 of about 413,499 (385)

Ferroptosis as a target for protection against cardiomyopathy

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Nonapoptotic cell death-induced tissue damage has been implicated in a variety of diseases, including neurodegenerative disorder, inflammation, and stroke.
X. Fang, Hao Wang, Dan Han, Enjun Xie, Xiang Yang, Jiayu Wei, Shanshan Gu, F. Gao, N. Zhu, Xiangju Yin, Qi Cheng, Pan Zhang, Wei Dai, Jinghai Chen, Fuquan Yang, Huang-Tian Yang, A. Linkermann, W. Gu, J. Min, Fudi Wang   +19 more
semanticscholar   +1 more source

Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis

Circulation Research, 2020
Supplemental Digital Content is available in the text. Rationale: Maintaining iron homeostasis is essential for proper cardiac function. Both iron deficiency and iron overload are associated with cardiomyopathy and heart failure via complex mechanisms ...
X. Fang, Zhaoxian Cai, Hao Wang, Dan Han, Qi Cheng, Pan Zhang, F. Gao, Yingying Yu, Zijun Song, Qian Wu, P. An, Sicong Huang, Jianwei Pan, Houzao Chen, Jinghai Chen, A. Linkermann, J. Min, Fudi Wang   +17 more
semanticscholar   +1 more source

Mitochondrial Determinants of Doxorubicin-Induced Cardiomyopathy.

Circulation Research, 2020
Anthracycline-based chemotherapy can result in the development of a cumulative and progressively developing cardiomyopathy. Doxorubicin is one of the most highly prescribed anthracyclines in the United States due to its broad spectrum of therapeutic ...
K. Wallace, V. Sardão, P. Oliveira
semanticscholar   +1 more source

Incremental Prognostic Utility of Left Ventricular Global Longitudinal Strain in Hypertrophic Obstructive Cardiomyopathy Patients and Preserved Left Ventricular Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundIn obstructive hypertrophic cardiomyopathy patients with preserved left ventricular (LV) ejection fraction, we sought to determine whether LV global longitudinal strain (LV‐GLS) provided incremental prognostic utility.
Albree Tower‐Rader, Jorge Betancor, Zoran B. Popovic, Kimi Sato, Maran Thamilarasan, Nicholas G. Smedira, Harry M. Lever, Milind Y. Desai   +7 more
doaj   +1 more source

High-Throughput Precision Phenotyping of Left Ventricular Hypertrophy with Cardiovascular Deep Learning [PDF]

, 2021
Left ventricular hypertrophy (LVH) results from chronic remodeling caused by a broad range of systemic and cardiovascular disease including hypertension, aortic stenosis, hypertrophic cardiomyopathy, and cardiac amyloidosis. Early detection and characterization of LVH can significantly impact patient care but is limited by under-recognition of ...
arxiv   +1 more source

Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy.

New England Journal of Medicine, 2015
BACKGROUND The natural history, management, and outcome of takotsubo (stress) cardiomyopathy are incompletely understood. METHODS The International Takotsubo Registry, a consortium of 26 centers in Europe and the United States, was established to ...
C. Templin, J. Ghadri, J. Diekmann, L. C. Napp, D. Bataiosu, M. Jaguszewski, V. L. Cammann, A. Sarcon, V. Geyer, C. Neumann, B. Seifert, J. Hellermann, Moritz Schwyzer, Katharina Eisenhardt, J. Jenewein, J. Franke, H. Katus, C. Burgdorf, H. Schunkert, C. Moeller, H. Thiele, J. Bauersachs, C. Tschöpe, H. Schultheiss, C. Laney, Lawrence Rajan, G. Michels, R. Pfister, C. Ukena, M. Böhm, R. Erbel, A. Cuneo, K. Kuck, C. Jacobshagen, G. Hasenfuss, M. Karakas, W. Koenig, W. Rottbauer, S. Said, R. Braun-Dullaeus, F. Cuculi, A. Banning, T. Fischer, T. Vasankari, K. Airaksinen, M. Fijałkowski, A. Rynkiewicz, M. Pawlak, G. Opolski, R. Dworakowski, P. MacCarthy, C. Kaiser, S. Osswald, L. Galiuto, F. Crea, W. Dichtl, W. Franz, K. Empen, S. Felix, C. Delmas, O. Lairez, P. Erne, Jeroen J. Bax, I. Ford, F. Ruschitzka, A. Prasad, T. Lüscher   +66 more
semanticscholar   +1 more source

Cardiomyopathies

Journal de Radiologie, 2004
Cardiomyopathies include a wide variety of cardiac diseases. The value of MR imaging is not only to provide information about cardiac function, but also to detect the underlying cause of the disease.
J P, Laissy, J N, Dacher, V, Sebban, O, Vignaux   +3 more
openaire   +4 more sources

Machine Learning Methods for Identifying Atrial Fibrillation Cases and Their Predictors in Patients With Hypertrophic Cardiomyopathy: The HCM-AF-Risk Model [PDF]

CJC Open, Volume 3, Issue 6, June 2021, Pages 801-813, 2021
Hypertrophic cardiomyopathy (HCM) patients have a high incidence of atrial fibrillation (AF) and increased stroke risk, even with low risk of congestive heart failure, hypertension, age, diabetes, previous stroke/transient ischemic attack scores. Hence, there is a need to understand the pathophysiology of AF and stroke in HCM.
arxiv   +1 more source

Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia: Proposed Modification of the Task Force Criteria

European Heart Journal, 2010
Background— In 1994, an International Task Force proposed criteria for the clinical diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) that facilitated recognition and interpretation of the frequently nonspecific clinical ...
F. Marcus, W. J. McKenna, D. Sherrill, C. Basso, B. Bauce, D. A. Bluemke, H. Calkins, D. Corrado, M. Cox, James P. Daubert, G. Fontaine, K. Gear, R. Hauer, A. Nava, Michael H. Picard, N. Protonotarios, J. Saffitz, Danita M. Yoerger Sanborn, Jonathan S. Steinberg, H. Tandri, G. Thiene, J. Towbin, A. Tsatsopoulou, T. Wichter, W. Zareba   +24 more
semanticscholar   +1 more source

Management of Acute Myocarditis and Chronic Inflammatory Cardiomyopathy

Circulation: Heart Failure, 2020
Supplemental Digital Content is available in the text.
E. Ammirati, M. Frigerio, E. Adler, C. Basso, D. Birnie, M. Brambatti, M. Friedrich, K. Klingel, J. Lehtonen, J. Moslehi, P. Pedrotti, O. Rimoldi, H. Schultheiss, C. Tschöpe, L. Cooper, P. Camici   +15 more
semanticscholar   +1 more source