Results 321 to 330 of about 413,499 (385)

Familial restrictive cardiomyopathy with novel missense variant of uncertain significance in the FLNC gene

ESC Heart Failure, EarlyView.
Ryo Nakayama, Toshikazu D. Tanaka, Shunsuke Inoue, Jun Yoshida, Jun Hasegawa, Tomohisa Nagoshi, Seitaro Nomura, Hiroyuki Morita, Michihiro Yoshimura   +8 more
wiley   +1 more source

Calpain inhibition in a transgenic model of calpastatin overexpression facilitates reversal of myocardial hypertrophy

ESC Heart Failure, EarlyView.
Abstract Aims It was recently demonstrated that the intracellular signalling phosphatase calcineurin is subject to cleavage by the protease calpain, resulting in a truncated calcineurin fragment that is a strong inductor of myocardial hypertrophy. We now address the question of whether inhibition of calpain function in cardiomyocytes, and thereby ...
Gregor Sachse, Johanna Tennigkeit, Nikolaos Pagonas, Philipp Hillmeister, Ivo Buschmann, Martin Czolbe, Peter Nordbeck, Joachim Schmitt, Daniel Patschan, Oliver Ritter   +9 more
wiley   +1 more source

Alcohol-Induced Cardiomyopathy Presenting With a Ventricular Arrhythmia Storm Causing Cardiac Arrest. [PDF]

Cureus
Ukponmwan EU, Banga S, Abela G.
europepmc   +1 more source

Electron microscopic findings predict clinical outcomes in patients with non‐ischaemic cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Aims Electron microscopy reveals microstructural alterations in cardiomyocyte nuclei and myofilaments in non‐ischaemic cardiomyopathy (NICM), particularly in dilated cardiomyopathy (DCM). Nevertheless, the correlation between such observations and clinical outcomes, including prognosis and left ventricular reverse remodelling (LVRR), remains ...
Rie Higuchi, Shozo Konishi, Tomohito Ohtani, Fusako Sera, Misato Chimura, Machiko Kanzaki, Themistoklis Katsimichas, Masahiro Seo, Tetsuya Watanabe, Takahiro Okumura, Toyoaki Murohara, Hiroyuki Takahama, Atsushi Okada, Chisato Izumi, Masaru Hatano, Issei Komuro, Yoshihiko Ikeda, Yoshihiro Asano, Hatsue Ishibashi‐Ueda, Yasushi Sakata   +19 more
wiley   +1 more source

Changes in peak oxygen consumption in Fabry disease and associations with cardiomyopathy severity. [PDF]

Heart
Roy A, Thompson SE, Hodson J, van Vliet J, Condon N, Alvior AM, O'Shea C, Vijapurapu R, Nightingale TE, Clift PF, Townend J, Geberhiwot T, Steeds RP.   +12 more
europepmc   +1 more source

Transthyretin amyloid cardiomyopathy in aortic stenosis patients scheduled for transcatheter aortic valve implantation

ESC Heart Failure, EarlyView.
Abbreviations: TAVI, transcatheter aortic valve implantation; ATTR‐CM, transthyretin cardiac amyloidosis. We aimed to diagnose occult ATTR‐CM in patients with severe aortic stenosis undergoing TAVI using bone scintigraphy. We verified a diagnosis of ATTR‐CM in 8 of 171 (4.7 %) consecutive aortic stenosis patients who underwent TAVI.
Margrethe Flesvig Holt, August Flø, Esra Kaya, Sophie Foss Kløve, Hege Martinsen, Kristine Amlie, Petter Storsten, Thomas Misje Mathiisen, Kristoffer Russell, Christian Hesbø Eek, Helge Skulstad, Melinda Raki, Lars Gullestad, Anders Hodt, Einar Gude, Kaspar Broch   +15 more
wiley   +1 more source

Clinical Validity of Autosomal DominantALPK3Loss-of-function Variants as a Cause of Hypertrophic Cardiomyopathy

Hespe S, Singer ES, Reuter C, Murray B, Jordan E, Chowns J, Peters S, Mayers M, Gray B, Hershberger RE, Owens A, Semsarian C, Waddell A, Asatryan B, Owens E, Thaxton C, Adduru M, Anderson K, Brown EE, Hoffman-Andrews L, Stafford F, Bagnall RD, Bronicki L, Callewaert B, Chahal CAA, James CA, Jarinova O, Landstrom AP, McNally EM, Muiño-Mosquera L, Parikh V, Walsh R, Wayburn B, Ware JS, Parker BL, Porrello ER, Elliott DA, McNamara JW, Ingles J.   +38 more
europepmc   +1 more source

The 'Padua classification' of cardiomyopathies into three groups: hypertrophic/restrictive, dilated/hypokinetic, and scarring/arrhythmogenic. [PDF]

Eur Heart J Suppl
Corrado D, Graziano F, Bauce B, Bueno Marinas M, Calore C, Celeghin R, Cipriani A, De Gaspari M, De Lazzari M, Migliore F, Perazzolo Marra M, Pilichou K, Rigato I, Rizzo S, Angelini A, Zorzi A, Thiene G, Basso C.   +17 more
europepmc   +1 more source

Discovering new hub genes of dilated cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified. The present study aimed to explore new hub genes of DCM by mining the human DCM databases and further by experimental validation.
Jun‐Yan Zhu, Yu Han, Jing‐Yu Yang, De‐Ping Wang, Li‐Juan Gao, Teng Sun, Yan‐Lin Feng, Zhong‐Mei He, Bin Zhou, Ji‐Min Cao   +9 more
wiley   +1 more source