Results 31 to 40 of about 439,002 (390)

Differences in molecular phenotype in mouse and human hypertrophic cardiomyopathy

open access: yesScientific Reports, 2021
Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity. We investigated the molecular basis of the cardiac phenotype in two mouse models at established disease stage (mouse-HCM), and human myectomy tissue (human-HCM).
Styliani Vakrou   +11 more
doaj   +1 more source

Time spent with cats is never wasted: Lessons learned from feline acromegalic cardiomyopathy, a naturally occurring animal model of the human disease [PDF]

open access: yes, 2018
BackgroundIn humans, acromegaly due to a pituitary somatotrophic adenoma is a recognized cause of increased left ventricular (LV) mass. Acromegalic cardiomyopathy is incompletely understood, and represents a major cause of morbidity and mortality.
A Colao   +80 more
core   +2 more sources

Peripartum Cardiomyopathy

open access: yesJournal of Education and Teaching in Emergency Medicine, 2023
This simulation is appropriate for emergency medicine (EM) residents of all levels.Peripartum cardiomyopathy (PPCM) is a rare, idiopathic condition that occurs in the mother around the time of childbirth. Heart failure with reduced ejection fraction and/or reduced systolic function diagnosed in patients during the last month of pregnancy or up to five ...
Morris, Victoria L   +4 more
openaire   +3 more sources

Molecular analysis of sarcomeric and non-sarcomeric genes in patients with hypertrophic cardiomyopathy. [PDF]

open access: yes, 2015
Background: Hypertrophic cardiomyopathy (HCM) is a common genetic heart disorder characterized by unexplained left ventricle hypertrophy associated with non-dilated ventricular chambers.
BOTTILLO, IRENE   +12 more
core   +1 more source

Mitochondrial Cardiomyopathies [PDF]

open access: yesFrontiers in Cardiovascular Medicine, 2016
Mitochondria are found in all nucleated human cells and perform various essential functions, including the generation of cellular energy. Mitochondria are under dual genome control. Only a small fraction of their proteins are encoded by mitochondrial DNA (mtDNA), whereas more than 99% of them are encoded by nuclear DNA (nDNA).
El-Hattab, Ayman W., Scaglia, Fernando
openaire   +3 more sources

Contemporary Insights Into the Genetics of Hypertrophic Cardiomyopathy: Toward a New Era in Clinical Testing?

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Genetic testing for hypertrophic cardiomyopathy (HCM) is an established clinical technique, supported by 30 years of research into its genetic etiology.
Francesco Mazzarotto   +6 more
doaj   +1 more source

Cirrhotic Cardiomyopathy

open access: yesJournal of the American College of Cardiology, 2010
Cirrhotic cardiomyopathy is a clinical syndrome in patients with liver cirrhosis characterized by an abnormal and blunted response to physiologic, pathologic, or pharmacologic stress but normal to increased cardiac output and contractility at rest. As many as 50% of cirrhotic patients undergoing liver transplantation show signs of cardiac dysfunction ...
Enrico M, Zardi   +8 more
openaire   +4 more sources

The prognostic value of clinical frailty scale and outcomes in older patients undergoing left ventricular assist device implantation

open access: yesAGING MEDICINE, Volume 5, Issue 4, Page 257-263, December 2022., 2022
The main finding in our study is that Clinical Frailty Scale‐defined frailty status was predictive of 1‐year post‐interventional mortality after left ventricular assist device implantation. Abstract Objectives Heart failure impacts patients’ functional capabilities, ultimately leading to frailty.
Temitope Ajibawo   +3 more
wiley   +1 more source

Prevalence of anxiety and depression symptoms in a sample of outpatients with ATTR cardiac amyloidosis

open access: yesFrontiers in Psychology, 2023
Patients with ATTR cardiac amyloidosis (ATTR-CA) face rare disease that could negatively influence psychological well-being with consequences on the course of the disease and quality of life.
Martina Smorti   +16 more
doaj   +1 more source

Cardiomyopathies in the elderly [PDF]

open access: yesJournal of the American College of Cardiology, 1987
Cardiomyopathies in the elderly have certain characteristic features. The dilated form appears to be less common than in younger patients. Hypertrophic cardiomyopathy is more often associated with severe and concentric hypertrophy. The prognosis of hypertrophic cardiomyopathy seems to be better in the elderly, because they appear to have a lower ...
Walter H. Abelmann   +2 more
openaire   +2 more sources

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