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Preparation of cardioplegic solutions

American Journal of Health-System Pharmacy, 1979
The manufacturing methods and quality control procedures for two cardioplegic solutions are described. Procedures for preparing individual bottles or batches of two cardioplegic solutions (one with and one without albumin) and a carbonate-bicarbonate buffer solution are described.
S, Armistead   +4 more
openaire   +2 more sources

Nifedipine stability in cardioplegic solution

American Journal of Health-System Pharmacy, 1984
The stability of nifedipine in cardioplegic solution was studied. Cardioplegic solutions containing nifedipine at 275 and 500 micrograms/liter were stored in plastic bags covered in brown plastic wrappers (1) under normal room light at 25 degrees C and (2) in a dark refrigerator at 4 degrees C. Samples were removed periodically for 48 hours.
M B, Bottorff   +4 more
openaire   +2 more sources

Retrieval of crystalloid cardioplegic solutions

The Annals of Thoracic Surgery, 1996
We describe a very simple method to minimize the systemic hemodilution associated with crystalloid cardioplegic solutions, either in an antegrade or retrograde fashion.
P M, Eucher   +3 more
openaire   +2 more sources

Vascular effects of potassium cardioplegic solutions

General Pharmacology: The Vascular System, 1983
Experiments have been performed on isolated human umbilical and sheep coronary arteries, studying the effects of increasing potassium concentration in steps from 10 to 160 mM. Comparative studies were also done on rat-heart papillary-muscle preparations. The results revealed a dose-dependent increase in smooth muscle tone of the blood vessels.
J S, Juggi   +4 more
openaire   +2 more sources

Regional Myocardial Perfusion of Cardioplegic Solutions

The Annals of Thoracic Surgery, 1987
We compared the regional myocardial perfusion of blood cardioplegic solution (BCP) and crystalloid cardioplegic solution (CCP) in 14 mongrel dogs. Cardiopulmonary bypass was established at 28 degrees C, and a hydraulic occluder was placed around the proximal left anterior descending (LAD) coronary artery. In group 1 (N = 7) collateral coronary arteries
J, Eugene   +6 more
openaire   +2 more sources

Maximal oxygenation of dilute blood Cardioplegic solution

The Annals of Thoracic Surgery, 1987
The content of dissolved O2 (the major source of O2 for the myocardium) of dilute blood cardioplegic solution (dBCS) varied widely when oxygenated at 4 degrees C by surface flow of O2 in a Bentley BCR-3500 cardiotomy reservoir. We have modified the system to consistently deliver maximally oxygenated dBCS to the heart.
W G, Hendren   +5 more
openaire   +2 more sources

The Optimal Potassium Concentration in Cardioplegic Solutions

The Annals of Thoracic Surgery, 1981
High-energy phosphates provide a sensitive index of myocardial preservation. This experiment was designed to use this index in order to assess the efficacy of various potassium concentrations in a crystalloid cardioplegic solution in protecting the myocardium during hypothermic ischemic arrest.
J H, Rousou   +3 more
openaire   +2 more sources

An Intracellular-like Cardioplegic Solution

Archives of Surgery, 1980
We sought to determine the relative protective effects of an intracellular-like, calcium-bearing, crystalloid solution (ICS) and a calcium-free, extracellular-like solution (ECS). Both solutions were similar in concentrations of potassium ions (25 to 26 mEq/L), in pH (7.7 to 7.8), and in osmolarity (340 to 360 mOsm/L).
I Y, Christlieb, R E, Clark
openaire   +2 more sources

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