Results 121 to 130 of about 7,833,346 (285)

Physiological, Performance and Perceptual Effects of Acute Intake of an L-Arginine and L-Citrulline Beverage Prior to a Repeated Bout of Intensive Running Among University Soccer Players

open access: yesNutraceuticals
The purpose of this study was to determine whether a combined L-arginine and L-citrulline beverage can enhance total nitric oxide (NOx), as well as physiological (cardiopulmonary metrics) and perceptual (rate of perceived exertion) responses to a ...
Siphamandla Nyawose   +3 more
doaj   +1 more source

Model‐Informed Dose Optimization of Anakinra in Preterm Neonates Implications for Safe and Effective Dosing

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Anakinra, an interleukin‐1 receptor antagonist, shows promise for reducing inflammatory complications of premature birth. However, the pharmacokinetics (PK) of anakinra in neonates has not been characterized, limiting evidence‐based dosing. This study aimed to develop a population PK model for anakinra to guide dosing in preterm neonates.
Jia Li   +27 more
wiley   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane   +4 more
wiley   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi   +9 more
wiley   +1 more source

Oxygen Uptake during daily life domestic activities in patients with Heart Failure and reduced ejection fraction

open access: yes, 2019
Background Dyspnea is a pivotal symptom of chronic heart failure with reduced ejection fraction (HFrEF). It seriously compromises exercise performance, capability to perform standard activities of daily living (ADLs) and quality of life. Cardiopulmonary
F. De Martino   +11 more
core   +1 more source

MELD score predicts outcomes in patients with advanced heart failure: A longitudinal evaluation

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 839-847, April 2025.
Abstract Aims Advanced heart failure (AHF) is characterized by recurrent episodes of haemodynamic instability and frequent hospitalizations, leading to a progressive decline in quality of life and high mortality rates. The objectives of this study were to evaluate the effect of the model for end‐stage liver disease (MELD) score and its variations in ...
Francesco Curcio   +10 more
wiley   +1 more source

Comprehensive exploration of unexplained dyspnoea in subjects with normal ejection fraction and low natriuretic peptides

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 879-887, April 2025.
Abstract Background Unexplained exertional dyspnoea without significant elevation of natriuretic peptides is common. One of the causes might be early heart failure with preserved ejection fraction (HFpEF). Aims This study aimed to characterize patients with exertional dyspnoea and normal/near‐to‐normal N‐terminal pro‐brain natriuretic peptide (NT ...
Emmanuelle Berthelot   +8 more
wiley   +1 more source

A Case of Vitamin D Defciency in a Young Athlete Diagnosed by Cardiopulmonary Exercise Test

open access: yesCase Reports in Clinical Practice, 2019
In this case report, we present a 16-year-old athlete woman with the history of dyspnea, especially during exercise with vitamin D deficiency that was diagnosed by cardiopulmonary exercise test.
Besharat Rahimi, Maryam Edalatifard
doaj  

Effect of cardiopulmonary rehabilitation exercise on old patients with chronic obstructive pulmonary disease and chronic heart failure

open access: yesZhongguo kangfu lilun yu shijian
Objective To observe the effect of cardiopulmonary rehabilitation exercise on exercise tolerance and quality of life in old patients with chronic obstructive pulmonary disease and chronic heart failure (COPD-CHF).
QI Li   +5 more
doaj   +1 more source

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