Results 71 to 80 of about 7,833,346 (285)

Prognostic Value of Submaximal Exercise Data for Cardiac Morbidity in Fontan Patients

, 2017
Introduction Submaximal exercise parameters are associated with an increased risk of hospitalization in patients with heart failure, but the implication in patients with Fontan circulation remains unknown.
邱英世;呂鴻基;盧俊維;陳益祥;王主科;林銘泰;陳俊安;吳美環;邱馨慧;陳思遠;張重義, Chen, Chun-An;Chen, Ssu-Yuan;Chiu, Hsin-Hui;Wang, Jou-Kou;Chang, Chung-I;Chiu, Ing-Sh;Chen, Yih-Sharng;Lu, Chun-Wei;Lin, Ming-Tai;Lue, Hung-Chi;Hua, Yu-Chuan;Wu, Mei-Hwan   +1 more
core   +1 more source

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET

Advanced Science, EarlyView.
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei, Tanja Groll, Stephanie Kahl, Silke Baer, Elisabeth Bliemsrieder, Frits H. A. van Heijster, Andre Wendlinger, Pascal Wodtke, Jorge Cabello, Susan Notohamiprodjo, Christian Lohrmann, Markus Schwaiger, Wolfgang A. Weber, Katja Steiger, Andrea Meyer‐Lindenberg, Johannes Hirschberger, Christine Baumgartner, Franz Schilling   +17 more
wiley   +1 more source

Alkylating Agent–Induced FANCL Impairment Damages Pulmonary Arterial, Venous, and Microvascular Endothelial Cells and Predisposes to PAH/PVOD

Advanced Science, EarlyView.
This study establishes a novel cisplatin‐induced rat model of PAH/PVOD and identifies a conserved mechanistic axis—FANCL impairment, DNA damage accumulation, and endothelial dysfunction—triggered by cisplatin or mitomycin C across pulmonary arteries, veins, and microvessels.
Shiyun Liu, Yufei Sun, Xinlei Wu, Haixia Chen, Shaocong Mo, Zichong Li, Yiwei Gong, Xiaoqian Shan, Yuanqi Li, Yaru Guan, Junqi Zhu, Han Yan, Min Du, Feng Wei, Peixin Ou, Ziyi Wang, Chenting Zhang, Lei Xu, Wenju Lu, Jian Wang, Kai Yang   +20 more
wiley   +1 more source

Development of Versatile Nanoparticle System for Efficient Drug Delivery into Pulmonary Endothelium

Advanced Science, EarlyView.
Pediatric acute respiratory distress syndrome (PARDS) suppresses the FOXF1 transcription factor and disrupts lung development. This study shows that the FOXF1‐activating small‐molecule compound, TanFe[F], can be precisely delivered to lung endothelial cells using the innovative LEDD nanoparticle system.
Afzaal N. Mohammed, Zicheng Deng, Arnab Misra, Marcus Orzabal, Ananya Kondapally, Enhong Li, Jonathan Do, Ying‐Wei Lan, Fatemeh Kohram, Hunter Blackburn, Andreas Damianos, Tanya V. Kalin, Vladimir V. Kalinichenko   +12 more
wiley   +1 more source

Apollo 14 Exercise Response Test [PDF]

, 1970
Document titled Apollo 14 Exercise Response Test notes the objective as "obtain data on crewmember's cardiopulmonary response to physical ...

core  

The Prospects of the Two-day Cardiopulmonary Exercise Test (CPET) in ME/CFS Patients: A Meta-Analysis

, 2020
Supplementary Tables and Figure for "The Prospects of the Two-day Cardiopulmonary Exercise Test (CPET) in ME/CFS Patients: A Meta ...
Eun-Jin Lim
core   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

Advanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin, Jian Lyu, Yanci Liu, Zhiyuan Feng, Jie Bao, Wenxiong Song, Bingcheng Zhu, Minghao Liu, Jionghao Xue, Jiadi Weng, Jiani Zhang, Jizong Zhao, Xiaolin Chen, Bin Dong   +13 more
wiley   +1 more source

Exercise may cause myocardial ischemia at the anaerobic threshold in cardiac rehabilitation programs

Brazilian Journal of Medical and Biological Research, 2009
Myocardial ischemia may occur during an exercise session in cardiac rehabilitation programs. However, it has not been established whether it is elicited when exercise prescription is based on heart rate corresponding to the anaerobic threshold as ...
A.R.C.N. Fuchs, R.S. Meneghelo, E. Stefanini, A.V. De Paola, P.E.P. Smanio, L.E. Mastrocolla, A.S. Ferraz, S. Buglia, L.S. Piegas, A.A.C. Carvalho   +9 more
doaj  

The Role of Cardiopulmonary Exercise Test in IPF Prognosis

Pulmonary Medicine, 2013
Background. In IPF, defects in lung mechanics and gas exchange manifest with exercise limitation due to dyspnea, the most prominent and disabling symptom. Aim.
Christina Triantafillidou, Effrosyni Manali, Panagiotis Lyberopoulos, Likourgos Kolilekas, Konstantinos Kagouridis, Sotirios Gyftopoulos, Konstantinos Vougas, Anastasia Kotanidou, Manos Alchanatis, Anna Karakatsani, Spyros A. Papiris   +10 more
doaj   +1 more source

High‐intensity exercise training improves perioperative risk stratification in the high‐risk patient

Physiological Reports, 2020
Exercise prehabilitation prior to major surgery can improve cardiorespiratory fitness (CRF) and clinical outcome. However, in patients deemed “high‐‐risk” for surgery, the feasibility, optimum training modality and its intensity, duration, and frequency ...
George A. Rose, Michael J. Adamson, Richard G. Davies, Ian R. Appadurai, Damian M. Bailey   +4 more
doaj   +1 more source