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Cardiorenal and hepatorenal syndrome
Journal of Pediatric Critical Care, 2018 Cardiorenal syndrome(CRS) is an interdependent involvement of the heart and the kidney that leads to high morbidity, recurrent readmissions and grave prognosis.
Anand Bhutada +3 more
doaj +1 more source
Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials
Experimental Physiology, EarlyView.Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler +2 more
wiley +1 more source
New Advances in Cardiorenal Syndrome—Ready for Prime Time?
, 2022 Cardiorenal Syndrome has become one pressing issue as far as hospitalizations are concerned [...
Pliquett, Rainer U., Rainer U. Pliquett
core +1 more source
SGLT2i in heart failure: Cardiorenal mechanisms, clinical evidence and translational perspectives
Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.SGLT2 inhibitors improve heart failure outcomes through integrated cardiorenal mechanisms. In the kidney, they reduce glucose and sodium reabsorption, promoting natriuresis, osmotic diuresis and renal protection. In the heart, they enhance myocardial energetics, reduce inflammation, oxidative stress, fibrosis and adverse remodelling, resulting in fewer
Jelica Grujic‐Milanovic +4 more
wiley +1 more source
Acta Physiologica, Volume 242, Issue 10, October 2026.ABSTRACT Aim This study aims to investigate whether the Fibroblast Growth Factor 23 (FGF23) modulates the electrical activity of sinoatrial (SAN) cells. The canonical function of FGF23 is to regulate body phosphorus and calcium homeostasis by activating the FGF1 receptors (FGFR1)/α‐Klotho complex in the kidney and parathyroid glands.
Giorgia Bertoli +10 more
wiley +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8812-8824, October 2026.ABSTRACT Aims Attaining target glycaemia can be a challenge in Type 1 Diabetes (T1D) due to insulin‐induced weight gain. Adjunct therapy with modern glucose‐lowering agents developed for type 2 diabetes (T2D) has great potential but may be insufficiently efficacious and carries risks of hypoglycaemia and ketosis.
Joseph G. Timmons +11 more
wiley +1 more source
A New Era in the Management of Cardiorenal Syndrome: The Importance of Cardiorenal Units [PDF]
Introduction: Approximately 70% of patients with heart failure (HF) also have kidney disease. Mortality is increased both by cardiorenal syndrome (CRS) and by the exacerbation of other comorbidities.
Zamora Carrillo, Jorge Ivan +19 more
core +1 more source
CARDIORENAL SYNDROME TYPE 2 – LITERATURE REVIEW [PDF]
, 2014 U srpnju 2013. godine proveli smo pretraživanje literature u bazi podataka Pubmed. Ključna riječ je bila kardiorenalni sindrom tip 2, a pretraživanje ograničeno na radove koji su napisani na engleskom jeziku i koje se odnose na ljude.
BAŠIĆ-JUKIĆ, NIKOLINA +4 more
core +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9461-9472, October 2026.ABSTRACT Aim Although finerenone has shown efficacy in randomized trials, evidence from routine clinical practice remains limited. We aimed to assess the real‐world effectiveness and safety of finerenone in people with type 2 diabetes (PWT2D) and chronic kidney disease (CKD), with a particular focus on residual cardiorenal risk as reflected by changes ...
Oscar Moreno‐Pérez +13 more
wiley +1 more source