Results 141 to 150 of about 2,866,241 (276)

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

open access: yesPediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

High‐intensity interval training vs. moderate‐intensity continuous training in COVID‐19 survivors (COVIDEX): A randomized clinical trial on feasibility and short‐term efficacy

open access: yesPM&R, EarlyView.
Abstract Background High‐intensity interval training (HIIT) and moderate‐intensity continuous training (MICT) have been widely studied in individuals with chronic conditions. However, no studies have compared these two exercise modalities in COVID‐19 survivors. Objective To compare the feasibility, safety, adherence, and short‐term efficacy of HIIT and
Vinicius Afonso Gomes   +11 more
wiley   +1 more source

A comprehensive Sustainable Development Goal‐guided framework for advancing survivorship, rehabilitation, and quality of life in breast cancer patients

open access: yesPrecision Medical Sciences, EarlyView.
This article presents an Sustainable Development Goal‐aligned framework integrating survivorship care, rehabilitation, and quality‐of‐life strategies for breast cancer patients, emphasizing equity, gender responsiveness, and health system strengthening. It highlights multidisciplinary, patient‐centered interventions and global partnerships as essential
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

open access: yesPhytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli   +6 more
wiley   +1 more source

Sleep‐disordered breathing in valvular heart disease: A Modifiable comorbidity

open access: yesSleep Research, EarlyView.
Abstract Sleep‐disordered breathing (SDB) is highly prevalent among patients with valvular heart disease (VHD) and is independently associated with adverse clinical outcomes. The two major phenotypes—obstructive sleep apnea (OSA) and central sleep apnea (CSA)—exhibit distinct distributions across VHD subtypes. CSA predominates in severe aortic stenosis,
Wu Juan   +6 more
wiley   +1 more source

Cardiorespiratory instability during sleep in infants: Physiological and developmental consequences

open access: yesSleep Research, EarlyView.
Abstract During fetal life, autonomic control of the cardio‐respiratory system undergoes rapid maturation and this continues after birth during the first year of life. This underlying immaturity of cardio‐respiratory control leads to an increased risk of cardio‐respiratory instabilities and resultant hypoxaemia during infancy.
Rosemary S. C. Horne
wiley   +1 more source

Novel assessment of cardiorespiratory interactions in aortic stenosis

open access: yes, 2018
The outcome in aortic stenosis (AS) depends on the correct timing of aortic valve replacement. Currently, this is based on symptoms and cardiac response to pressure overload. In patients with multiple medical conditions, uncertainty exists concerning their symptomatic onset and in distinguishing cardiac from respiratory causes of breathlessness.
openaire   +2 more sources

Human‐Centered Monitoring of Asphalt Emissions: Linking Exposure, Climate, and Health

open access: yesSafety Science and Technology, EarlyView.
A human‐centered framework linking heat‐driven asphalt emissions to real‐world exposure, biological response, and functional health outcomes, highlighting how climate‐sensitive infrastructure can become a measurable, manageable source of urban environmental and health risk. ABSTRACT Urban infrastructure shapes environmental quality not only through its
Suliman Rashid   +6 more
wiley   +1 more source

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

open access: yesVIEW, EarlyView.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf   +5 more
wiley   +1 more source

The Global Airways Unit: A Multidisciplinary Strategy for Early Diagnosis and Comorbidity Detection

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic respiratory diseases impose a large global burden of morbidity, mortality, and cost. The concept of a global airway has become increasingly supported by epidemiologic, mechanistic, and clinical evidence. However, clinical care often remains fragmented between ear, nose, and throat (ENT), allergy, and pulmonology.
Diego M. Conti   +16 more
wiley   +1 more source

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