Results 41 to 50 of about 1,503,374 (259)

Developing an intervention to optimise the outcome of cardiac surgery in people with diabetes: the OCTOPuS pilot study

Pilot and Feasibility Studies, 2021
Background Cardiothoracic surgical outcomes are poorer in people with diabetes compared with those without diabetes. There are two important uncertainties in the management of people with diabetes undergoing major surgery: (1) how to improve diabetes ...
Richard I. G. Holt, Katharine Barnard-Kelly, Giorgos Dritsakis, Kerensa I. Thorne, Lauren Cohen, Elizabeth Dixon, Mayank Patel, Philip Newland-Jones, Helen Partridge, Suvitesh Luthra, Sunil Ohri, Kareem Salhiyyah, Jo Picot, John Niven, Andrew Cook, on behalf of the OCTOPuS study group   +15 more
doaj   +1 more source

Cardiothoracic Surgery in the Caribbean

, 2023
Introduction: Despite being one of the main vacation destinations in the world, health care in the Caribbean faces many difficulties. The challenges involved in these islands’ medical care range from low-resource institutions to lack of specialized care.
Peterson, Tim F., Cardiovascular Centre (CVC), Vinck, Eric E., Ebels, Tjark; id_orcid, Dr. Horacio Oduber Hospital, Clínica Cardio VID, Martinique University Hospital, Hittinger, Romain   +7 more
core   +1 more source

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

Advanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk, Leanne Van den Berg, Isa B. M. Velraeds, Valentina Osorio Zuluaga, Emma T. M. Peereboom, Martijn J. W. E. Rabelink, Arnaud Zaldumbide, Rob C. Hoeben, Marie‐Jose T. H. Goumans, Eric Spierings, Carlijn V. C. Bouten, Marijn C. Peters   +11 more
wiley   +1 more source

Surgical skills assessment during resident selection process: Survey of American cardiothoracic and Canadian cardiac surgery program directorsCentral MessagePerspective

JTCVS Open
Objective: Matching into cardiothoracic and cardiac surgery training programs is highly competitive. As surgical simulation becomes increasingly accessible, we present the various perspectives of program directors (PDs) on the potential assessment of ...
Klaudiusz Stoklosa, MD, Elie Fadel, MDCM(c), Terrence M. Yau, MDCM, MSc   +2 more
doaj   +1 more source

Surgical repair of complete atrioventricular defect (Nunn technique)

, 2015
Two procedures have been traditionally used for the surgical repair of complete atrioventricular canal. The single-patch technique includes the division of valve leaflets, and the use of one patch to close the ventricular and the atrial septal defects ...
Arabi, Mariam Toufic, Tabbakh, Anas M., El-Rassi, Issam M., Charafeddine, Fatme, Bitar, Fadi Fouad, Aboutaka, Mohammad, Khater, Daniele   +6 more
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

A General High‐Throughput Mucus Microrheology Platform for Quantitative and Scalable Mucus Phenotyping

Advanced Science, EarlyView.
High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling, Ayşe Tuğçe Şahin, Bernardo Miller Naranjo, Stefano Aime, Doris Roth, Anna Pukaluk, Niels Tepho, Romina Augustin, Benedetta Zampa, Andrea S. Vendrame, Mark‐Christian Klassen, Ellen Emken, Marion Kiechle, Mircea Gabriel Stoleriu, Pontus Mertsch, Ruth Olmer, Yohannes Tesfaigzi, Oliver Lieleg, Janna C. Nawroth   +18 more
wiley   +1 more source

Factors affecting timing of surgery following neoadjuvant chemoradiation for esophageal cancer

Heliyon, 2023
Background: Neoadjuvant chemoradiation with esophagectomy is standard management for locally advanced esophageal cancer. Studies have shown that surgical timing following chemoradiation is important for minimizing postoperative complications, however in ...
Shannon J. Jiang, Andrada C. Diaconescu, Dyke P. McEwen, Laura N. McEwen, Andrew C. Chang, Jules Lin, Rishindra M. Reddy, William R. Lynch, Sidra Bonner, Kiran H. Lagisetty   +9 more
doaj   +1 more source

Sexual Harassment and Cardiothoracic Surgery: #UsToo?

, 2019
Background Fifty-eight percent of women in science, engineering, and medicine report being affected by sexual harassment (SH). This study sought to determine the extent of SH in cardiothoracic surgery.
Boden, Natalie, Dolejs, Scott C., Blackmon, Shanda, Ceppa, DuyKhanh P., Yost, Katherine J., Phelan, Sean, Donington, Jessica, Naunheim, Keith S.   +7 more
core   +1 more source

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

Advanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng, Zijun Meng, Lan Wei, Pingjing Yang, Fanfan Zhang, Zhiyi Luo, Ting Lai, Chunli Li, Mengyao Zhao, Mengqin Xu, Jiaqi Wang, Linjun Li, Huarong Chen, Jin Li, Ailong Huang, Youquan Bu, Liuyang Zhao   +16 more
wiley   +1 more source