Results 111 to 120 of about 5,087,575 (343)

The orphan receptor GPR35 contributes to angiotensin II–induced hypertension and cardiac dysfunction in mice [PDF]

, 2018
BACKGROUND: The orphan receptor G protein–coupled receptor 35 (GPR35) has been associated with a range of diseases, including cancer, inflammatory bowel disease, diabetes, hypertension, and heart failure.
Divorty, Nina, Graham, Delyth, Milligan, Graeme, Nicklin, Stuart A.   +3 more
core   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

IVIG Resistance in Kawasaki Disease: Clinical and Laboratory Risk Factors and the Potential Role of Administration Timing

Journal of Inflammation Research
Yue Peng,1– 3,* Fengchuan Jing,1– 3,* Dong Liu,4 Bin Li,5 Yanxia Xu,6 Zhongyou Tan,7 Ouyang Chen,7 Yanfeng Yang,8 Feifei Si,8 Wenliang Jiang,9 Cong Li,9 Zhenli Cheng,1– 3 Xue Zhou,1– 3 Siqi Feng,1– 3 Ya Su,1– 3 Qijian Yi1– 3 1Department ...
Peng Y, Jing F, Liu D, Li B, Xu Y, Tan Z, Chen O, Yang Y, Si F, Jiang W, Li C, Cheng Z, Zhou X, Feng S, Su Y, Yi Q   +15 more
doaj  

Sex Differences in Cardiovascular Outcomes in CKD: Findings From the CRIC Study

, 2021
Stephanie M. Toth‐Manikowski, Wei Yang, Lawrence J. Appel, Jing Chen, Rajat Deo, Anne Frydrych, Marie Krousel‐Wood, Mahboob Rahman, Sylvia E. Rosas, Daohang Sha, Jackson T. Wright, Martha L. Daviglus, Alan S. Go, James P. Lash, Ana C. Ricardo, Harold I. Feldman, Jiang He, Robert G. Nelson, Panduranga S. Rao, Vallabh O. Shah, Raymond R. Townsend, Mark L. Unruh   +21 more
openalex   +2 more sources

Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics. [PDF]

, 2020
Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for regenerative therapy, disease modeling, and drug discovery.
Chandy, Mark, Paik, David T, Wu, Joseph C   +2 more
core  

Temperature enhanced effects of ozone on cardiovascular mortality in 95 large US communities, 1987-2000 - assessment using the NMMAPS data [PDF]

, 2009
A few studies examined interactive effects between air pollution and temperature on health outcomes. This study is to examine if temperature modified effects of ozone and cardiovascular mortality in 95 large US cities.
Cizao Ren, Gail M. Williams, Kerrie Mengersen, Lidia Morawska, Ren C, Sharma H S, Shilu Tong   +6 more
core   +2 more sources

Amyotrophic Lateral Sclerosis Prevalence Projection in 2040: A Less Rare Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To project ALS prevalence across multiple countries through 2040, accounting for both population aging and increased survival. Methods Data from the Piemonte and Valle d'Aosta ALS register (PARALS) was used to estimate the trends in incidence and prevalence from 2005 to 2019. Survival trends over this period were also assessed.
Rosario Vasta, Stefano Callegaro, Antonio Canosa, Umberto Manera, Maurizio Grassano, Francesca Palumbo, Sara Cabras, Enrico Matteoni, Francesca Di Pede, Filippo De Mattei, Salvatore Tafaro, Neil M. Thakur, Ryan Grosenick, Fabiola De Marchi, Letizia Mazzini, Cristina Moglia, Andrea Calvo, Kuldip D. Dave, Adriano Chiò   +18 more
wiley   +1 more source

Bibliometric Analysis of microRNA: A Comprehensive Evaluation of Its Contribution to Acute Coronary Syndromes

Journal of Multidisciplinary Healthcare
Yuqian Gao,1,* Tianli Li,2,* Xiaohong Mu,1,* Xiaoxia Ren,1 Jing Wang,1 Jiasai Fan,1 Haiyan Zhu,1,3 Xian Wang1,3 1Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2National ...
Gao Y, Li T, Mu X, Ren X, Wang J, Fan J, Zhu H, Wang X   +7 more
doaj  

Mechanistic validation of the 2016 American Society of Echocardiography/European Association of Cardiovascular Imaging Guidelines for the assessment of diastolic dysfunction in heart failure with reduced ejection fraction [PDF]

, 2020
Ythan Goldberg, David Megyessi, Mischa Flam, Daniel M. Spevack, Martin Sundqvist, Martin Ugander   +5 more
openalex   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source