Results 141 to 150 of about 1,450,409 (287)

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

open access: yesAdvanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae   +5 more
wiley   +1 more source

Electrocardiographic Abnormalities and Reclassification of Cardiovascular Risk: Insights from NHANES-III

open access: yes, 2013
We aimed to assess the additive value of electrocardiogram (ECG) findings to risk prediction models for cardiovascular disease. Our dataset consisted of 6025 individuals with ECG data available from the National Health and Nutrition Examination Survey ...
Patel, Nileshkumar   +8 more
core   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen   +7 more
wiley   +1 more source

Association of Angiotensin Receptor Autoantibodies With Cardiovascular Abnormalities in Preeclampsia. [PDF]

open access: yesJ Am Heart Assoc, 2021
Minhas AS   +8 more
europepmc   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem   +24 more
wiley   +1 more source

Subclinical left ventricular systolic dysfunction and incident stroke in the elderly: long-term findings from Cardiovascular Abnormalities and Brain Lesions. [PDF]

open access: yesEur Heart J Cardiovasc Imaging, 2023
Yoshida Y   +13 more
europepmc   +1 more source

Self‐Powered All‐in‐One Wearable Bioelectronics Driven by Pneumatic Energy Buffering of Daily Footsteps

open access: yesAdvanced Science, EarlyView.
A pneumatic energy‐buffering strategy transforms transient and intermittent footsteps into quasi‐continuous electrical energy for a self‐powered wearable biosensing platform. The footwear‐integrated air‐pumping harvester, combined with the rationally designed power‐management system, powers a wearable ankle PPG device with reduced motion artifacts ...
Ji‐Seok Kim   +8 more
wiley   +1 more source

Subtle Cardiovascular Abnormalities in Prader-Willi Syndrome Might Begin in Young Adulthood. [PDF]

open access: yesIntern Med, 2021
Kobayashi S   +14 more
europepmc   +1 more source

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