Results 131 to 140 of about 648,624 (244)

Exploration of metformin-based drug combination for mitigating diabetes-associated atherosclerotic diseases. [PDF]

World J Diabetes
Qu B, Li Z, Hu W.
europepmc   +1 more source

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

Advanced Science, EarlyView.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li, Qi Xiang, Yan Zhang, Fuxue Luo, Yunfang Wu, Haitao Ran, Yang Cao   +6 more
wiley   +1 more source

Pillars of Blood Pressure Management in Patients with Type 2 Diabetes Mellitus: Insights from Recent Trials and Emerging Perspectives. [PDF]

J Clin Med
Pop C, Petriş AO, Pop L, David LE.
europepmc   +1 more source

Tailored 3D Lattice Microstructures for Enhanced Functionality in Blood‐Gas Exchange

Advanced Science, EarlyView.
Common hollow fiber structures are associated with inhomogeneous flow, leading to many complications in the medical application of extracorporeal membrane oxygenation. Using locally adapted lattice structures, the overall flow distribution can be manipulated.
Kai P. Barbian, Teresa Lemainque, Ina Grunden, Roman Iwa, Bettina Wiegmann, John Linkhorst, Matthias Wessling, Jan Heyer, Ulrich Steinseifer, Michael Neidlin, Sebastian V. Jansen   +10 more
wiley   +1 more source

Association between cumulative changes of the triglyceride glucose index and incidence of stroke in a population with cardiovascular-kidney-metabolic syndrome stage 0-3: a nationwide prospective cohort study. [PDF]

Cardiovasc Diabetol
Lu L, Chen Y, Liu B, Li X, Wang J, Nie Z, Fu X.   +6 more
europepmc   +1 more source

A Dual‐Modal Wearable Pulse Detection System Integrated with Deep Learning for High‐Accuracy and Low‐Power Sleep Apnea Monitoring

Advanced Science, EarlyView.
A dual‐modal wearable pulse detection system is developed for sleep apnea monitoring by integrating a self‐powered PENG and PPG sensor with a biomimetic fingertip structure. Through a two‐stage detection strategy, continuous PPW monitoring and on‐demand PPG detection achieve high‐accuracy sleep apnea recognition while maintaining low power consumption.
Jia Wang, Jiangtao Xue, Yang Zou, Yuxin Ma, Junhan Xu, Yanming Li, Fei Deng, Yiqian Wang, Kai Xing, Zhou Li, Tong Zou   +10 more
wiley   +1 more source

Glucagon-like peptide-1 receptor agonists: a review from a cardiovascular perspective. [PDF]

Front Cardiovasc Med
Turkistani Y.
europepmc   +1 more source

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

Advanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan, Jingyi Qi, Yi Xia, Chang Fan, Teng Xu, Xu Zhang, Jiaxin Shi, Chenxuan Wang, Yitong Cheng, Dongyuan Zhang, Rong Liu, Yinhua Zhu, Changchang Cao, Dekui Jin, Peng An, Yongting Luo, Junjie Luo   +16 more
wiley   +1 more source

Targeting lipoprotein(a): Pharmacotherapy in focus. [PDF]

Eur Heart J Cardiovasc Pharmacother
Tan DS, Ooi ZH, Lew CSF.
europepmc   +1 more source

Mechanical Stress Induced NOX2 Promotes Endothelial Dysfunction in Ventilator‐Induced Lung Injury: Potential Treatment with Quercetin

Advanced Science, EarlyView.
Abnormal mechanical stretch induced by mechanical ventilation (MV) disrupts endothelial junctions via the NOX2/ROS/CaMKII/ERK1/2 axis both in human aortic endothelial cells (HAECs) in vitro and in ventilator‐induced lung injury (VILI) in mice. Quercetin, an antioxidant predicted to bind to NOX2, can effectively prevent mechanical stretch‐induced ...
Tao Jiang, Yabing Zhang, Zhiye Guo, He Ren, Weiyi Hu, Qingping Yao, Yunlong Huo, Yingxin Qi, Kai Huang   +8 more
wiley   +1 more source