Results 231 to 240 of about 4,824,048 (369)

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source

Expert Consensus Document on the Use of Antiplatelet Agents The Task Force on the Use of Antiplatelet Agents in Patients with Atherosclerotic Cardiovascular Disease of the European Society of Cardiology

, 2003
Carlo Patrono
openalex   +1 more source

Is There Evidence That Oral Hypoglycemic Agents Reduce Cardiovascular Morbidity or Mortality? No [PDF]

, 2009
Sameer Kassem, Itamar Raz
openalex   +1 more source

Cardiovascular risk management beyond statins: review of new therapies available in Italy. [PDF]

Egypt Heart J
Capuozzo M, Ottaiano A, Cinque C, Farace S, Ferrara F.   +4 more
europepmc   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, Volume 12, Issue 28, July 24, 2025.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Prescribing Patterns of SGLT2 Inhibitors and GLP-1 Receptor Agonists in Patients With T2DM and ASCVD in South Korea. [PDF]

Pharmacoepidemiol Drug Saf
Eom YR, Joo H, Chae SE, Je NK.
europepmc   +1 more source

MCT1‐mediated Lactate Shuttle to Mitochondria Governs Macrophage Polarization and Modulates Glucose Homeostasis by Affecting β Cells

Advanced Science, EarlyView.
This study demonstrates that the transport of lactate to the mitochondria is of critical importance in determining the functions of macrophages by altering mitochondrial respiration. In macrophages, this lactate transport mechanism regulates glucose homeostasis by influencing the functions of insulin‐secreting cells in the pancreatic islets.
Lingling Chen, Yijun Lin, Xinyu Zhu, Shixuan Zhuo, Zixuan Li, Cheng Guo, Xiaoyi Ye, Jinzhu Chen, Shuying Wang, Yan Chen   +9 more
wiley   +1 more source

Development of a Synthetic Drug Information Database for Cardiovascular Agents

, 2003
Yuta Kasahara, Harumi Takada, Michiya Kobayashi, Shinji Kawai, Osamu Ogino, Mitsuru Sugawara, Akira Sekikawa, Katsumi Miyazaki   +7 more
openalex   +2 more sources

Effects of gadolinium contrast agent on aortic blood flow and myocardial strain measurements by phase-contrast cardiovascular magnetic resonance [PDF]

, 2010
Erik Hedström, Karin Markenroth Bloch, Erik Bergvall, Freddy Ståhlberg, Håkan Arheden   +4 more
openalex   +1 more source

Management of dyslipidaemia in patients with comorbidities-facing the challenge: type 1 diabetes mellitus. [PDF]

Eur Heart J Cardiovasc Pharmacother
Kaser S, Dobrev D, Rocca B, Kaski JC, Agewall S, Drexel H.   +5 more
europepmc   +1 more source