Results 251 to 260 of about 4,824,048 (369)

Synchrotron Radiation‐Based Tomography of an Entire Mouse Brain with Sub‐Micron Voxels: Augmenting Interactive Brain Atlases with Terabyte Data

Advanced Science, Volume 12, Issue 28, July 24, 2025.
Extended‐field acquisition enables sub‐micron X‐ray imaging of a full mouse brain. The 3.3‐teravoxel volume is reconstructed, registered to a reference atlas, and stored in hierarchical format to augment currently available atlases and improve resolution in the third dimension by an order of magnitude.
Mattia Humbel, Christine Tanner, Marta Girona Alarcón, Georg Schulz, Timm Weitkamp, Mario Scheel, Vartan Kurtcuoglu, Bert Müller, Griffin Rodgers   +8 more
wiley   +1 more source

Cardiovascular Events and Death in Children Exposed and Unexposed to ADHD Agents [PDF]

, 2011
Hedi Schelleman, Warren B. Bilker, Brian L. Strom, Stephen E. Kimmel, Craig Newcomb, James P. Guevara, Gregory W. Daniel, Mark J. Cziraky, Sean Hennessy   +8 more
openalex   +1 more source

Risk of Cardiovascular Disease in Cancer Survivors after Systemic Treatment: A Population-Based Cohort Study. [PDF]

JACC CardioOncol
Mulder FI, Horváth-Puhó E, van Es N, Pedersen L, Büller HR, Cronin-Fenton D, Christiansen CF, Bøtker HE, Bhaskaran K, Sørensen HT.   +9 more
europepmc   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source

Endothelial Progenitor Cells in Cardiovascular Disease and Chronic Inflammation: from Biomarker to Therapeutic Agent [PDF]

, 2011
Johannes Grisar, François Haddad, Fatemeh A. Gomari, Joseph C. Wu   +3 more
openalex   +1 more source

Optimizing Nephron Performance: The Old, the New, and the New-Old Diuretic Therapies. [PDF]

Biomedicines
Fuchs FD, Procianoy GS, Bottino LG, Fuchs SC, Whelton PK.   +4 more
europepmc   +1 more source

Microphysiological Uremia Model Reveals Biophysical Potentiators of Vascular Dysfunction

Advanced Science, EarlyView.
A microfluidic platform of engineered blood vessels is developed to study the role of mechanical forces in immune cell adhesion and extravasation in uremic microenvironments. Elevated pressure increases monocyte activity, with ICAM‐1 as a key driver. Matrix density influences monocyte phenotypes, but the uremic environment consistently promoted a pro ...
Mitesh Rathod, Ryan N. Stack, Sarah E. Kubik, Stephanie A. Huang, Chloe P. Whitworth, Wen Y. Aw, Elizabeth L. Doherty, Sara M. Meehan, Prabir Roy‐Chaudhury, William J. Polacheck   +9 more
wiley   +1 more source

In Vitro and In Vivo Synergism between Tetracycline and the Cardiovascular Agent Oxyfedrine HCl against Common Bacterial Strains

, 2005
Kaushiki Mazumdar, Noton K. Dutta, K. Asok Kumar, Sujata G. Dastidar   +3 more
openalex   +2 more sources

Systemic Effects of Intravitreal Anti-VEGF Therapy: A Review of Safety across Organ Systems. [PDF]

Ophthalmol Ther
Banerjee M, Moharana S, Padhy SK.
europepmc   +1 more source

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source