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Corrigendum to "Herceptin-Mediated Cardiotoxicity: Assessment by Cardiovascular Magnetic Resonance". [PDF]
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Therapeutic potential of chalcones as cardiovascular agents
Life Sciences, 2016Cardiovascular diseases are the leading cause of death affecting 17.3 million people across the globe and are estimated to affect 23.3 million people by year 2030. In recent years, about 7.3 million people died due to coronary heart disease, 9.4 million deaths due to high blood pressure and 6.2 million due to stroke, where obesity and atherosclerotic ...
Debarshi Kar Mahapatra+1 more
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Cardiovascular Protection with Anti-hyperglycemic Agents
American Journal of Cardiovascular Drugs, 2019Diabetes mellitus is a major risk factor for cardiovascular (CV) disease. Conversely, CV disease is responsible for a majority of the deaths in patients with diabetes. Many drug trials have concentrated on blood glucose (hemoglobin A1c) reduction. This strategy, while reducing microvascular outcomes like nephropathy and neuropathy, has little or no ...
Prakash Deedwania, Tushar Acharya
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Quinazoline cardiovascular agents (review)
Pharmaceutical Chemistry Journal, 1982The chemistry of quinazoline compounds has a more than centuries-old history; however, the intensive search for biologically active substances in this series began only in the last few decades. The establishment of the quinazoline structure of the antimalarial alkaloid febrifugine [i], which was isolated from the Chinese plant aseru (Dichroa febrifuga ...
O. N. Volzhina, L. N. Yakhontov
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Methods for Identifying Cardiovascular Agents: A Review
Recent Patents on Cardiovascular Drug Discovery, 2006Basic and clinical investigation into many of the diverse aspects of cardiovascular drug discovery employs varied approaches aimed at determining physiologic and pathophysiologic efficacy of candidate agents for therapeutic utility with the ultimate hope of identifying those agents capable of exerting salutary influence upon cardiac and vascular ...
D. Tulis
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American Heart Journal, 1994
The intranasal administration of drugs has long been used for the topical treatment of various nasal disorders. Many features of the intranasal mucosa also make it useful for delivery of systemically active agents. It has been shown that intranasal drug administration can provide plasma drug levels similar to those observed with comparable doses of ...
William H. Frishman+2 more
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The intranasal administration of drugs has long been used for the topical treatment of various nasal disorders. Many features of the intranasal mucosa also make it useful for delivery of systemically active agents. It has been shown that intranasal drug administration can provide plasma drug levels similar to those observed with comparable doses of ...
William H. Frishman+2 more
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Cardiovascular adjustment to antiadrenergic agents
The American Journal of Medicine, 1983A common target organ involvement associated with essential hypertension is left ventricular hypertrophy. A number of, but not all, effective antihypertensive drugs will regress left ventricular hypertrophy. Our attention has focused on the hemodynamic characteristics of those drugs that either directly or indirectly alter sympathetic nervous activity.
Edward D. Frohlich, Barbara L. Pegram
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Oral Antidiabetic Agents and Cardiovascular Outcomes
Current Problems in Cardiology, 2018Cardiovascular disease is the leading cause of morbidity and mortality among patients with type 2 diabetes; however, a direct protective effect of tight glycemic control remains unproven. In fact, until 2008, when concerns related to rosiglitazone prompted regulatory agencies to mandate assessment of cardiovascular safety of new antidiabetic agents ...
Pareek, Manan, Bhatt, Deepak L
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