Results 341 to 350 of about 4,836,823 (371)
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Organic and biomolecular chemistry, 2008
The amino acid proline catalyzed the three- and five-component cascade olefination-Diels-Alder-epimerization and olefination-Diels-Alder-epimerization-olefination-hydrogenation reactions of readily available precursors enones 1a-i, arylaldehydes 2a-k ...
Dhevalapally B. Ramachary +2 more
semanticscholar +1 more source
The amino acid proline catalyzed the three- and five-component cascade olefination-Diels-Alder-epimerization and olefination-Diels-Alder-epimerization-olefination-hydrogenation reactions of readily available precursors enones 1a-i, arylaldehydes 2a-k ...
Dhevalapally B. Ramachary +2 more
semanticscholar +1 more source
Cardiovascular toxicity of molecularly targeted agents
European Journal of Cancer, 2009Over the last decade, molecularly targeted drugs have become established in oncology therapeutics and clinical research. While initially marketed as “cancer specific” agents with superior toxicity profiles to conventional anti-proliferative and DNA-damaging chemotherapy, it has become increasingly apparent that these drugs have numerous serious “on ...
Elizabeth Laureen Strevel +1 more
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Urokinase-a Very Popular Cardiovascular Agent
Recent Patents on Cardiovascular Drug Discovery, 2008Urokinase (UK) [EC 3.4.99.26] is a serine protease that activates plasminogen to plasmin, which in turn degrades fibrin clots. Hence, UK finds its value as an important anti-thromboembolic drug. Plasmin has diverse physiological roles apart from its fibrinolytic role in the regulation of blood clotting.
Poluri Ellaiah +4 more
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Circulation Research, 2002
Nitric oxide (NO) mediates multiple physiological and pathophysiological processes in the cardiovascular system. Pharmacological compounds that release NO have been useful tools for evaluating the pivotal role of NO in cardiovascular physiology and ...
L. Ignarro, C. Napoli, J. Loscalzo
semanticscholar +1 more source
Nitric oxide (NO) mediates multiple physiological and pathophysiological processes in the cardiovascular system. Pharmacological compounds that release NO have been useful tools for evaluating the pivotal role of NO in cardiovascular physiology and ...
L. Ignarro, C. Napoli, J. Loscalzo
semanticscholar +1 more source
Recent advances in biotransformation of CNS and cardiovascular agents.
Current drug metabolism, 2000Compound biotransformation is a very important research area for drug discovery and development. In this review, publications from the metabolism studies of ten compounds, seven CNS and three cardiovascular agents, from the Johnson & Johnson Corp.
Wu Wn, McKown La
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Cardiovascular Effects of Intravenous Anesthetic Agents [PDF]
, 1985 The most commonly used anesthetic agents of this kind are the barbiturates. The duration of action of these agents is tied to their fat solubility. Since the thiobarbiturates are more fat soluble (classified as ultra-short acting), they provide a surgical plane of anesthesia for less time than the short acting agents such as pentobarbital sodium.
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Novel Antiplatelet Agents in Cardiovascular Medicine
Current Treatment Options in Cardiovascular Medicine, 2015Dual antiplatelet therapy with aspirin and a P2Y12 receptor blocker, particularly clopidogrel, has been the standard of therapy for secondary prevention in patients with acute coronary syndromes and patients treated with percutaneous coronary intervention.
Fang Liu +4 more
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Pharmacological activity of cardiovascular agents from herbal medicine.
Cardiovascular & Hematological Agents in Medicinal Chemistry, 2007Some of the active phytochemicals in herbal medicine are finding therapeutic use. For example, patients with heart disease are reported to benefit from treatment with herbal medicine with fewer side effects. Previous studies showed the inhibitory effects
J. Ho, Meng Jie
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Contrast Agents for Cardiovascular MRI
2008In the last two decades, magnetic resonance imaging (MRI) has revolutionized clinical cardiovascular imaging. Its major advantages over other noninvasive diagnostic modalities are its safety, operator-independent reproducibility, and multiplanar two-dimensional (2D) and three-dimensional (3D) imaging capability with high spatial and temporal resolution.
Frank J. Rybicki +4 more
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