Results 81 to 90 of about 447,481 (255)

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon   +5 more
wiley   +1 more source

Development of Multifunctional Hierarchically Restructured Antibacterial Neural Interfacing Electrodes via Plasma‐Enhanced Atomic Layer Deposition of Zinc Oxide Thin Films

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Next‐generation implantable neural‐interfacing devices are increasingly constrained by the coupled demands of electrode miniaturization, electrochemical performance, and implantation infection risk. Femtosecond laser–based hierarchical surface restructuring (HSR) technology has emerged as a scalable, manufacturing‐compatible platform for ...
Henna Khosla   +12 more
wiley   +1 more source

Polymer Substrates for Flexible Sensors: Advances and Contributions to Smart Agriculture

open access: yesAdvanced Functional Materials, EarlyView.
This review comprehensively summarizes recent advances in polymer‐based flexible sensors for smart agriculture, focusing on polymer substrate design, interface engineering, and applications in soil, plant, animal, aquaculture, and post‐harvest monitoring.
Yihui Li   +12 more
wiley   +1 more source

Optimal blood pressure control with fewer antihypertensive medications: Achieved mostly in low‐risk hypertensive patients

open access: yesThe Journal of Clinical Hypertension
Recent studies indicate that intensive blood pressure (BP) targets can be reached with less than two medications. This cross‐sectional study, involving 4991 individuals from the Majiapu community, assessed the correlation between BP control and the ...
Zhanyang Zhou   +5 more
doaj   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

Incretin analogues as cardiovascular agents: a state-of-the-art review

open access: yesFrontiers in Endocrinology
Glucagon-like peptide-1 (GLP-1) receptor agonists and the dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist tirzepatide have evolved over the past decade from glucose-lowering antidiabetic agents into a cardiovascular ...
Diego Araiza-Garaygordobil   +6 more
doaj   +1 more source

Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This paper proposes hydrogel microtube carriers composed of barium alginate gel, enabling long‐term vascular retention without interrupting blood flow. Intravascular treatments have long been attracting attention for therapeutic efficacy, yet practical delivery methods remained unestablished.
Shota Sato   +8 more
wiley   +1 more source

EFECTOS DE LOS MEDICAMENTOS CARDIOVASCULARES SOBRE EL GLOBO OCULAR / Effects of cardiovascular drugs on the eyeball [PDF]

open access: yesCorSalud, 2013
Resumen Introducción y objetivos: A las consultas de Oftalmología acuden pacientes con una alta incidencia de enfermedades cardiovasculares y muchos de los fármacos útiles para este tipo de afecciones pueden producir efectos indeseables sobre el globo ...
Caridad Peraza Martínez   +3 more
doaj  

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

Cardiovascular Safety Landscape of ADT in Prostate Cancer Treatment Based on Real‐World Analysis

open access: yesCancer Medicine
Background Prostate cancer is among the most prevalent malignancies worldwide, and cardiovascular disease (CVD) is a major non‐cancer cause of death in affected patients. Androgen deprivation therapy (ADT), a mainstay treatment, has raised concerns about
Wei Wang   +7 more
doaj   +1 more source

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