Results 241 to 250 of about 3,754,903 (381)

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

Advanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai, Yuxin Zhao, Zilong Li, Liping Xiao, Yifan Wu, Shiya Wang, Qian Liu, Yida Ye, Yuxuan Guo, Donghui Zhang   +9 more
wiley   +1 more source

Persistent Monocytic Bioenergetic Impairment and Mitochondrial DNA Damage in PASC Patients with Cardiovascular Complications. [PDF]

Int J Mol Sci
Semo D, Shomanova Z, Sindermann J, Mohr M, Evers G, Motloch LJ, Reinecke H, Godfrey R, Pistulli R.   +8 more
europepmc   +1 more source

An Off‐the‐Shelf Artificial Blood Clot Hydrogel Neutralizing Multiple Proinflammatory Mediators for Pro‐Regenerative Periodontitis Treatment

Advanced Science, EarlyView.
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu, Zhezhe Zhao, Xiang Liu, Jingrong Wang, Yufeng Zhang, Tingting Lan, Yonglan Wang, Chenxuan Wu, Ju Zhang, Pingsheng Huang, Chuangnian Zhang, Anjie Dong, Zujian Feng, Deling Kong, Weiwei Wang   +14 more
wiley   +1 more source

Novel biomarker panel combined with imaging parameters for predicting cardiovascular complications in diabetic patients: a retrospective cohort study. [PDF]

BMC Cardiovasc Disord
Guo J, Zhang Z.
europepmc   +1 more source

ER‐phagy Activation by AMFR Attenuates Cardiac Fibrosis Post‐Myocardial Infarction via mTORC1 Pathway

Advanced Science, EarlyView.
By catalyzing FAM134B ubiquitination and activating ER‐phagy, AMFR alleviates progressive fibrosis and cardiac dysfunction by inhibiting the mTORC1 pathway. Consequently, these findings underscore the essential role of AMFR‐driven ER‐phagy in mitigating the progression of fibrotic responses, offering a potential therapeutic target for preventing heart ...
Zhixiang Wang, Kaifan Niu, Wei Liu, Xinyun Wang, Boshen Yang, Taixi Li, Yizhi Chen, Yuanyuan Jin, Yu Chen, Yangyi Lin, Xian Jin   +10 more
wiley   +1 more source

ASA and severity of postoperative pain are prognostic factors for postoperative cardiovascular and respiratory complications

, 2002
Despina Dermitzaki, Fotini Chaniotaki, J. Kamarianakis, O. Fraidakis, Αλεξάνδρα Παπαϊωάννου, Helen Askitopoulou   +5 more
openalex   +1 more source

Cimetidine and cardiovascular complications. [PDF]

BMJ, 1979
openaire   +3 more sources

Immunocompatible Elastomer With Enhanced Fibrous Capsule‐Resistance and Elasticity by Water‐Induced Surface Phase Reconfiguration.

Advanced Science, EarlyView.
This study introduces a strategy for engineering heterogeneous surface and bulk structures within a single material, termed phase‐separation and underwater reconfiguration‐enhanced (PURE) elastomers. These elastomers combine high bulk elasticity with enhanced immunocompatibility at the surface.
Xianchi Zhou, Wenzhong Cao, Weifeng Liu, Wenbin Dai, Zihao Zhu, Fan Jia, Haijie Han, Ke Yao, Youxiang Wang, Jian Ji, Peng Zhang   +10 more
wiley   +1 more source

Microalbuminuria and Cardiovascular Events in Elderly Hypertensive patients without Previous Cardiovascular Complications

, 2003
Satoko Nakamura, Yuhei Kawano, Takashi Inenaga, Hajime Nakahama, Takeshi Horio, Osamu Sasaki, Naoki Okuda, Shuichi Takishita   +7 more
openalex   +2 more sources

Critical cardiovascular complications during non-immunosuppressive therapy for VEXAS syndrome. [PDF]

Rheumatol Adv Pract
Saito Y, Suzuki S, Ikeda K, Morimoto S.
europepmc   +1 more source