Results 81 to 90 of about 3,754,903 (381)

SurgiCal Obesity Treatment Study (SCOTS): protocol for a national prospective cohort study of patients undergoing bariatric surgery in Scotland. [PDF]

, 2015
Introduction The efficacy of bariatric surgery for large-scale, long-term weight loss is well established. However, many questions remain over the continual benefits and cost-effectiveness of that weight loss for overall health, particularly when ...
Abrams, Babor, Barry, Belle, Bruce, Courcoulas, Craig, Derby, Foster, Health Protection Scotland, Keating, Kolotkin, Macran, Mercer, O'Brien, Picot, Roe, Scheier, Shikora, Spitzer, Spitzer, Wadden, Ware, Welbourn, Williams   +24 more
core   +4 more sources

Physical Exercise and Myokines: Relationships with Sarcopenia and Cardiovascular Complications

International Journal of Molecular Sciences, 2020
Skeletal muscle is capable of secreting different factors in order to communicate with other tissues. These mediators, the myokines, show potentially far-reaching effects on non-muscle tissues and can provide a molecular interaction between muscle and ...
S. Barbalho, Uri Adrian Prync Flato, R. J. Tofano, R. Goulart, É. Guiguer, C. Detregiachi, D. Buchaim, A. Araújo, R. Buchaim, F. Reina, Piero Biteli, Daniela O B Rodrigues Reina, M. Bechara   +12 more
semanticscholar   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Cardiovascular complications of COVID-19

Journal of V. N. Karazin Kharkiv National University: Series Medicine
Background. The problem of COVID-19 today is the most unresolved worldwide. Scientists and doctors all over the world are trying to study features of pathogenesis this disease to find the most effective treatment methods.
N.V. Bila, M.S. Brynza, N.V. Tytarenko
doaj   +1 more source

Cardiovascular complications of chemotherapy: A synopsis

SA Heart Journal, 2017
It is important to identify chemotherapy-related cardiotoxicity as it may impact on the overall survival of cancer patients. The various forms of cardiotoxicity encountered during and after chemotherapy for cancer, include impaired left ventricular ...
Len Steingo
doaj   +1 more source

Timing of bariatric surgery in people with obesity and diabetes [PDF]

, 2015
The use of bariatric surgery in the clinical management of type 2 diabetes in severely obese subjects has been included in the clinical practice recommendations released by the most influential diabetologic associations.
Busetto, Luca
core   +1 more source

Cardiovascular Complications of Systemic Therapy in Non-Small-Cell Lung Cancer

Journal of Clinical Medicine, 2020
Cardiovascular diseases may determine therapy outcomes of non-small-cell lung cancer (NSCLC). The evidence for how iatrogenic cardiovascular complications contribute to ceasing anticancer treatment, decreasing the quality of life or even premature death,
M. Zaborowska-Szmit, M. Krzakowski, D. Kowalski, S. Szmit   +3 more
semanticscholar   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Risk of cardiovascular disease and total mortality in adults with type 1 diabetes: Scottish registry linkage study [PDF]

, 2012
<p>Background: Randomized controlled trials have shown the importance of tight glucose control in type 1 diabetes (T1DM), but few recent studies have evaluated the risk of cardiovascular disease (CVD) and all-cause mortality among adults with T1DM.
Andrew D. Morris, Donald W. M. Pearson, Eleanor J. Hothersall, Frank Sullivan, Graham P. Leese, Helen C. Looker, Helen M. Colhoun, John Chalmers, John McKnight, John R. Petrie, Naveed Sattar, Norman R. Peden, Richard Lehman, Robert S. Lindsay, Sam Philip, Sarah H. Wild, Shona J. Livingstone, Stephen Cleland   +17 more
core   +6 more sources