Results 91 to 100 of about 6,863,547 (308)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Should socioeconomic factors be considered as traditional risk factors for cardiovascular disease, as confounders, or as risk modifiers? [PDF]

, 2008
A large number of studies show that cardiovascular disease and its traditional risk factors are associated with socioeconomic conditions. However, their etiological role in the development of cardiovascular outcomes is not always well understood ...
Marmot, M., De Vogli, R.
core  

Menopause and cardiovascular disease

Journal of Mid-life Health, 2019
Menopausal health demand priority in Indian scenario due to increase in life expectancy and growing population of menopausal women. Time demands to promote a multidisciplinary, multi-factorial, comprehensive approach to the care of these women. By the medium of this editorial and our experience in dealing women in advancing age in and around menopause,
Annil Mahajan, Ranu Patni, Varun Gupta
openaire   +3 more sources

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Clinical characteristics and survival of Chinese patients diagnosed with pulmonary arterial hypertension who carry BMPR2 or EIF2KAK4 variants

BMC Pulmonary Medicine, 2020
Background Variants in the gene encoding bone morphogenetic protein receptor type II (BMPR2) are the most common genetic cause of pulmonary arterial hypertension (PAH), whereas biallelic variants in the eukaryotic translation initiation factor 2 alpha ...
Qixian Zeng, Hang Yang, Bingyang Liu, Yanyun Ma, Zhihong Liu, Qianlong Chen, Wenke Li, Qin Luo, Zhihui Zhao, Zhou Zhou, Changming Xiong   +10 more
doaj   +1 more source

Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY. [PDF]

, 2010
The unparalleled collection of clinical data and biomaterials within the EHDN's REGISTRY can expedite the search for disease modifiers (genetic and environmental) of age at onset and disease progression that could be harnessed for the development of ...
Handley, Olivia J, Landwehrmeyer, G Bernhard, Aileen K Ho, Bisson, Jonathan Ian, Schwenke C, David Craufurd, Dunnett, Stephen B., Handley, Olivia, Investigators of the European Huntington's Disease Network, The, DI MARIA, EMILIO, Craufurd D, Dunnett, SB, Carsten Schwenke, the investigators of the European Huntington's Disease Network, Craufurd, David, Edward Wild, Landwehrmeyer, GB, Busse, Monica, Rosser, Anne Elizabeth, Olivia J Handley, Romano Silvia., Tabrizi SJ, Ho, Aileen K., Wild, E, Landwehrmeyer GB, Craufurd, D, Tabrizi, SJ, Tabrizi, Sarah J., Handley, OJ, Rickards, Hugh, Dunnett, Stephen, Ho, Aileen K, Orth, Michael, Ho, AK, Wild, Edward, Stephen B. Dunnett, Sarah J Tabrizi, Wild, EJ, Landwehrmeyer, G. Bernhard, Naji, Jenny, Landwehrmeyer, G. Bernhard, Wild E, Investigators of the European Huntington's Disease Network, Handley, Olivia J., Orth, M, Ellison-Rose, Lynda, Tabrizi, Sarah J, Price, Kathleen, Ho AK, ABBRUZZESE, GIOVANNI, Schwenke, C, Ho, A, Orth M, Handley OJ, Schwenke, Carsten, Dunnett SB, Dunnett, Stephen B, Michael Orth, G. Bernhard Landwehrmeyer   +59 more
core   +1 more source

Targeting the CD47-SIRPα Axis in Atherosclerosis: From Pathogenesis to Therapeutic Implications

Journal of Inflammation Research
ChangXin Sun,1,2,* Lanqing Hu,2,* Yongfang Yuan,2 Kaidong Zhou,2 Min Wu,3 Longtao Liu2,31School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, 100029, People’s Republic of China; 2State Key Laboratory of ...
Sun C, Hu L, Yuan Y, Zhou K, Wu M, Liu L
doaj  

Significant association between elevated urine albumin-to-creatinine ratio and increased risk of acute coronary syndrome: a retrospective cross-sectional analysis

Annals of Medicine
Background Acute coronary syndrome (ACS) is a major cause of mortality worldwide. Chronic kidney disease (CKD) is associated with cardiovascular disease.
Yujie Song, Fangying Yan, Yangjie Yu, Junjie Pan, Wei Shen, Huanchun Ni, Jian Li, Xinping Luo, Yong Li, Haiming Shi, Liwen Bao   +10 more
doaj   +1 more source

Measurement of interatrial septal thickness by echocardiography in patients with moderate to severe rheumatic mitral stenosis undergoing percutaneous balloon mitral valvuloplasty

International Journal of Cardiology: Heart & Vasculature, 2019
Background: Longstanding severe rheumatic mitral stenosis (MS) is associated with changes in the atrial chamber dimensions. It is not known whether there is an increased thickness of the inter-atrial septum (IAS) in patients with severe rheumatic mitral ...
Faisal Qadir, Tariq Ashraf, Kanwal Fatima Aamir, Abdul Samad Achakzai, Syed Muhammad Afaque, Muhammad Nauman Khan, Najia Aslam Soomro, Simran Salman Qureshi, Musa Karim   +8 more
doaj   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source