Results 121 to 130 of about 10,789,024 (363)

Endothelial major vault protein alleviates vascular remodeling via promoting Parkin-mediated mitophagy

Nature Communications
Many important vascular diseases including neointimal hyperplasia and atherosclerosis are characterized by the endothelial cell (EC) injury-initiated pathological vascular remodeling.
Bin Jiang, Fan Bai, Yunfu Hu, Yu Ren, Yuan Su, Wanxuan Song, Kunxin Xie, Dongdong Wang, Junlu Pan, Yuying Liu, Yuxin Feng, Xiaoyu Li, Hanwen Zhang, Xudong Zhu, Hui Bai, Qing Yang, Jingjing Ben, Qi Chen   +17 more
doaj   +1 more source

Statistical Studies of Heart Disease: IX. Race and Sex Differences in the Trend of Mortality from the Major Cardiovascular-Renal Diseases [PDF]

, 1951
Iwao M. Moriyama, Theodore D. Woolsey
openalex   +1 more source

Time trends and predictors of gout remission over six years

Arthritis Care &Research, Accepted Article.
Objectives This study aims to describe the trends in remission rates over six years of follow‐up among people with gout taking urate‐lowering therapy (ULT), and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES ...
Adwoa Dansoa Tabi‐Amponsah, Sarah Stewart, Greg Gamble, Lisa K Stamp, William J Taylor, Nicola Dalbeth   +5 more
wiley   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Four new mutations in the apolipoprotein B gene causing hypobetalipoproteinemia, including two different frameshift mutations that yield truncated apolipoprotein B proteins of identical length.

Journal of Lipid Research, 1993
Familial hypobetalipoproteinemia can be caused by mutations in the apolipoprotein (apo)B gene that interfere with the translation of a full-length apoB molecule. Frequently, a truncated apoB molecule can be detected in the plasma lipoproteins of affected
SG Young, CR Pullinger, BR Zysow, H Hofmann-Radvani, MF Linton, RV Farese, Jr, JF Terdiman, SM Snyder, SM Grundy, GL Vega   +9 more
doaj  

The Weight of the Heart and Its Chambers in Hypertensive Cardiovascular Disease with and without Failure [PDF]

, 1953
Russell S. Jones
openalex   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Functional Cardiovascular Disease [PDF]

, 1948
Meyer Friedman
openalex   +1 more source

Key Trends and Insights in Smart Polymeric Skin Wearable Patches

Advanced Engineering Materials, EarlyView.
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez, Rajat Rai, Miryam Criado‐Gonzalez   +2 more
wiley   +1 more source

Cardiovascular Disease in Cotton Workers: Part I [PDF]

, 1951
Robert Schilling, Nancy Goodman
openalex   +1 more source