Results 161 to 170 of about 6,876,447 (305)

Physical activity evaluation handbook [PDF]

U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Division of Nutrition and Physical Activity.Spiral-bound.Also available ...
National Center for Chronic Disease Prevention and Health Promotion (U.S.)
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Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Modifiable Lifestyle Factors in Cardiovascular Disease Prevention: Current Evidence and Future Directions. [PDF]

Nutrients
Benjamin P, Djoussé L.
europepmc   +1 more source

State heart disease and stroke prevention evaluation framework

"Recognizing the immense burden of cardiovascular disease (CVD), Congress made funding available in FY 1998 to initiate a national, state-based CVD prevention program.

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BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

Advanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu, Ruo‐xin Wang, Feng He, Qian Liu, Fu‐yin Li, Min Hui, Yu‐qian Shi, Yu Jiang, Qing‐hua Li, Jun‐wen Jing, Shi‐bin Yu, Li‐tian Ma, Qian‐nan Niu, Mian Zhang   +13 more
wiley   +1 more source

Discrepancies in low-value practices across cardiovascular disease prevention guidelines. A narrative review. [PDF]

Eur J Gen Pract
Brotons C, Moral I, Axelrod T, Brodersen JB, Martins C, Öztora S, Petričušić I, Piessens V, Reyes C, Rodriguez-Benito L, Terebessi A.   +10 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Evidence and opportunities for preeclampsia and cardiovascular disease prevention in malaria endemic settings. [PDF]

Commun Med (Lond)
Obionu IM, Moore JM, Zahradeen S, Galadanci H, Huffman MD, Mahmoud Z.   +5 more
europepmc   +1 more source

What's new in cardiovascular prevention ?

, 2007
This review is essentially a summary of the 2007 version of the European guidelines on cardiovascular disease prevention in clinical practice recently published by the 4(th) Joint Task Force.
Brohet, Christian, 4th Joint European Guidelines on Cardiovascular Disease Prevention in Clinical Practice   +1 more
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