Results 211 to 220 of about 1,487,366 (315)

FTO in cardiovascular diseases: mechanisms, context dependence, and translational opportunities. [PDF]

Front Cell Dev Biol
Kong Y, Zhang D.
europepmc   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Role of eRNAs in Cardiovascular Diseases. [PDF]

Curr Cardiol Rev
Li Y, Song C, Cui J, Fei X, Lei X, Tang H.   +5 more
europepmc   +1 more source

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source

Deep Learning and Cardiovascular Diseases: An Updated Narrative Review. [PDF]

J Clin Med
Myśliwiec A, Bartusik-Aebisher D, Xavierselvan M, Paul A, Aebisher D.   +4 more
europepmc   +1 more source

In Vivo Microplastic Detection With Photoacoustic Imaging

Advanced Science, EarlyView.
ABSTRACT Microplastics are posing an escalating threat to both ecological systems and human health. Yet, current methods for investigating their bioaccumulation are highly invasive, requiring destructive analysis of ex vivo tissues via mass spectrometry, dye labelling, or Raman microspectroscopy.
Joseph C. Bear, Olumide Ogunlade, Jayvian Mavi, Emily J. Deniszczyc, Daolong Chen, Heeva Javaheri, Paul Beard, Mark F. Lythgoe, Daniel J. Stuckey, P. Stephen Patrick   +9 more
wiley   +1 more source

Familial coaggregation and shared genetic loading of mental disorders and cardiovascular diseases. [PDF]

Psychol Med
Chen PC, Pan YJ, Lin MC, Su MH, Fan CC, Wu CS, Wang SH.   +6 more
europepmc   +1 more source

Anomalous Origin of the Right Coronary Artery/circumflex from the Pulmonary Artery (ARPACA) - Exercise Induced VT

Journal of Cardiovascular Magnetic Resonance
Vladimir Mihajlovic, MD, Ljiljana Rankovic-Nicic, MD, Milica Dragicevic-Antonic, MD, Snezana Tajic, MD, Zelimir Antonic, MD, Maja Pirnat, PhD, FSCMR, Goran Loncar, MD, PhD, Robert Manka, MD, FSCMR   +7 more
doaj   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Recent Advances in the Diagnosis and Management of Cardiovascular Diseases: A Comprehensive Review. [PDF]

Cureus
Sen N, Singh NK, Patil SA, Sridevi A, Modani SM, Rampelly SK.   +5 more
europepmc   +1 more source