Results 71 to 80 of about 1,370,177 (306)

Incidence rate of recurrent cardiovascular events in patients with radiographic axial spondyloarthritis and the effect of tumor necrosis factor inhibitors

Arthritis Research & Therapy
Background Patients with radiographic axial spondyloarthritis (r-axSpA) are at increased risk of incident cardiovascular events. Tumor necrosis factor inhibitors (TNFi) have shown a protective effect against incident cardiovacular events.
Oh Chan Kwon, Hye Sun Lee, So Young Jeon, Min-Chan Park   +3 more
doaj   +1 more source

Does sticky blood predict a sticky end? Associations of blood viscosity, haematocrit and fibrinogen with mortality in the West of Scotland [PDF]

, 2003
There is increasing evidence that blood viscosity and its major determinants (haematocrit, plasma viscosity and fibrinogen) are associated with an increased risk of incident cardiovascular events; however, their associations with mortality are not ...
Ann Rumley, Danesh, Danesh, Gordon D. O. Lowe, Heart Protection Study Collaborative Group, Hugh Tunstall-Pedoe, Koenig, Lee, Lee, Lowe, Lowe, Lowe, Lowe, Lowe, Lowe, Lowe, Lowe, Mark Woodward, Meade, Millar, Progress Collaborative Group, Rose, Smith, Smith, Sweetnam, Tunstall-Pedoe, Von Clauss, Wannamethee, Woodward, Woodward   +29 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Life events and hemodynamic stress reactivity in the middle-aged and elderly [PDF]

, 2005
Recent versions of the reactivity hypothesis, which consider it to be the product of stress exposure and exaggerated haemodynamic reactions to stress that confers cardiovascular disease risk, assume that reactivity is independent of the experience of ...
Aiken L. S., Allen M. T., Benschop R. J., Boyce W. T., Brown G. W., Cacioppo J. T., Carroll D., Carroll D., Carroll D., Everson S. A., Eysenck H. J., Lepore S. J., Light K. C., Linden W., Lynch J. W., Manuck S. B., Markovitz J. H., Matthews K. A., Matthews K. A., Musante L., Phillips A. C., Pike J. L., Registrar General, Treiber F. A., Treiber F. A., West S. G.   +25 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Cardiovascular Adverse Events Reported in Placebo Arm of Randomized Controlled Trials in Parkinson’s Disease

Journal of Parkinson’s Disease, 2020
Background: Parkinson’s disease and cardiovascular disease are highly prevalent conditions in the elderly. Evidence shows inconsistent findings regarding the association between Parkinson’s disease and cardiovascular events.
Mariana Alves, Daniel Caldeira, Miguel Leal Rato, Gonçalo S. Duarte, Afonso N. Ferreira, José Ferro, Joaquim J. Ferreira   +6 more
doaj   +1 more source

Carotid atherosclerotic disease predicts cardiovascular events in hemodialysis patients: a prospective study. [PDF]

PLoS ONE, 2015
To evaluate the predictive value of carotid atherosclerotic disease (CAD) and intima-media thickness (IMT) on incident cardiovascular disease and mortality in hemodialysis patients.Multicenter, observational, prospective study including 110 patients ...
Sílvia Collado, Elisabeth Coll, Carlos Nicolau, Mercedes Pons, Josep M Cruzado, Julio Pascual, Aleix Cases   +6 more
doaj   +1 more source

Electronic circuit detects left ventricular ejection events in cardiovascular system [PDF]

, 1972
Electronic circuit processes arterial blood pressure waveform to produce discrete signals that coincide with beginning and end of left ventricular ejection. Output signals provide timing signals for computers that monitor cardiovascular systems.
Gebben, V. D., Webb, J. A., Jr.
core   +1 more source

Biomarkers, Atherosclerosis and Cardiovascular Events [PDF]

Expert Review of Cardiovascular Therapy, 2008
The 57th Annual Scientific Session of the American College of Cardiology was held in Chicago (IL, USA) between 29 March and 1 April 2008. It was attended by nearly 30,000 participants from around the world. The conference was highlighted by the presentation of 13 late-breaking clinical trials and 13 late-breaking abstracts.
openaire   +2 more sources

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source