Results 101 to 110 of about 2,278,438 (306)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Climate Change and Cardiovascular Health: Environmental Stressors, Mechanistic Insights, and Clinical Perspectives

Reviews in Cardiovascular Medicine
Climate change poses a significant threat to cardiovascular health through the combined effects of extreme temperatures, air pollution, and extreme weather events.
Tingting Lv, Qing Liu, Yifei Wang, Ping Zhang   +3 more
doaj   +1 more source

The Cardiovascular Effects of Cocoa Polyphenols—An Overview

Diseases, 2016
Cocoa is a rich source of high-quality antioxidant polyphenols. They comprise mainly catechins (29%–38% of total polyphenols), anthocyanins (4% of total polyphenols) and proanthocyanidins (58%–65% of total polyphenols). A growing body of experimental and
Ana Clara Aprotosoaie, Anca Miron, Adriana Trifan, Vlad Simon Luca, Irina-Iuliana Costache   +4 more
doaj   +1 more source

Walks4work: Rationale and study design to investigate walking at lunchtime in the workplace setting [PDF]

, 2012
Background: Following recruitment of a private sector company, an 8week lunchtime walking intervention was implemented to examine the effect of the intervention on modifiable cardiovascular disease risk factors, and further to see if walking environment ...
A Alwan, A Puig-Ribera, AJ Hautala, AJ Minisi, AJ Nelson, BJ Park, C Tudor-Locke, CB Chan, CL Craig, CR Cole, CR Cole, D Watson, Daniel K Brown, Department of Health, Department_of_Health, DP Zipes, DR Seals, EK Nisbet, EM Murtagh, EO Nishime, G Borg, GE Billman, GE Duncan, GJ Welk, GR Sandercock, H Hemingway, H Tsuji, HE Brown, I Hess, J Barton, J Barton, J Pretty, J Pretty, J Pretty, J Stevens, Jo L Barton, JP Buckley, Jules Pretty, K Sykes, KY Chen, LW Rystedt, M Rosenberg, MH Murphy, MS Penn, MT La Rovere, MT La Rovere, N Gilson, NA King, Q Li, R Rosmond, RP Juster, RW Hoyt, S Cohen, S Ogoh, SB Racette, SN Blair, T Chandola, T Cox, T Hartig, Task Force, Valerie F Gladwell, VF Gladwell, VS Conn, WB Schaufeli, WB Schaufeli, WHO, WHO, WHO, WL Haskell, X Jouven   +69 more
core   +2 more sources

Changing cardiovascular health: national cardiovascular health policy 2010-2019

, 2010
This new cardiovascular policy, Changing Cardiovascular Health covering the period 2010-2019, comes a decade after the first national cardiovascular health strategy, entitled Building Healthier Hearts, was published by the Department of Health in 1999.
openaire   +3 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

RNA Modifications in Health and Disease

MedComm
RNA modifications, including N6‐methyladenosine (m6A), 5‐methylcytosine, and pseudouridine, serve as pivotal regulators of gene expression with significant implications for human health and disease.
Shiqi Li, Ping Luo, Junli Fan, Yirong Li, Jiancheng Tu, Xinghua Long   +5 more
doaj   +1 more source

Association between cardiovascular parameters (blood pressure, heart rate, and heart rate reserve) and physical activity level in school-aged adolescents in Marrakech region, Morocco

Journal of Education and Health Promotion
Background: Cardiovascular parameters are critical determinants in the onset and progression of circulatory diseases, including hypertension and heart disease, which remain among the leading causes of mortality in Morocco.
Abdelmoujoud El Haboussi, Bilal El-Mansoury, Abdelaati El Khiat, Mohamed-Kamal Hilali, Mohamed Loukid   +4 more
doaj   +1 more source

Cocaine addiction severity exacerbates the negative association of lifetime lead exposure with blood pressure levels: Evidence from a pilot study

Environmental Disease, 2019
Background: High blood pressure (BP) is associated independently with cocaine use and lead exposure. It is not known whether cocaine use and lead exposure act jointly to disrupt cardiovascular health.
Elena Colicino, Danielle B Hazeltine, Kelly M Schneider, Anna Zilverstand, Keren Bachi, Nelly Alia-Klein, Rita Z Goldstein, Andy C Todd, Megan K Horton   +8 more
doaj   +1 more source

Extra virgin olive oil and cardiovascular diseases: benefits for human health [PDF]

, 2017
The cardioprotective properties of Mediterranean Diet were demonstrated for the first time from the Seven Country Study. In the last few decades, numerous epidemiological studies, as well as intervention trial, confirmed this observation, pointing out ...
Cammisotto, Vittoria, Carnevale, Roberto, Castellani, Valentina, D'Amico, Alessandra, Fianchini, Luca, Nocella, Cristina, Novo, Marta, Stefanini, Lucia, Violi, Francesco   +8 more
core   +1 more source