Results 21 to 30 of about 164,933 (217)

Left ventricular strain derived from cardiac magnetic resonance can predict outcomes of pulmonary valve replacement in patients with repaired tetralogy of Fallot

Frontiers in Cardiovascular Medicine, 2022
PurposeSeveral adults with repaired tetralogy of Fallot (rToF) undergo pulmonary valve replacement (PVR) to reduce the right ventricular volume and retain right ventricular function.
Baiyan Zhuang, Shiqin Yu, Zicong Feng, Fengpu He, Yong Jiang, Yong Jiang, Shihua Zhao, Minjie Lu, Minjie Lu, Shoujun Li   +9 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Comparative Evaluation of Cardiac Sarcoidosis, Giant Cell Myocarditis, and Arrhythmogenic Right Ventricular Cardiomyopathy on Cardiac Magnetic Resonance

Cardiology Discovery
. Objective:. Diagnosing cardiac sarcoidosis (CS), giant cell myocarditis (GCM), and arrhythmogenic right ventricular cardiomyopathy (ARVC) is difficult because all 3 cardiomyopathies can involve both the right and left ventricles, leading to ...
Yun Tang, Yan Xing, Jinghui Li, Yanyan Song, Jiaxin Wang, Shujuan Yang, Shiqin Yu, Zhixiang Dong, Xuan Ma, Kai Yang, Xiuyu Chen, Shihua Zhao, Hanjia Gao   +12 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Left ventricular remodeling index to predict ventricular tachyarrhythmia in dilated cardiomyopathy with ejection fraction < 35%

Insights into Imaging
Objectives To assess the left ventricular remodeling index (LVRI) for predicting ventricular tachyarrhythmia (VTA) in patients with dilated cardiomyopathy (DCM) with left ventricular ejection fraction (LVEF) 
Xi Jia, Weipeng Yan, Xuan Ma, Zhixiang Dong, Jiaxin Wang, Shujuan Yang, Kankan Zhao, Zhuxin Wei, Yun Tang, Pengyu Zhou, Xingrui Chen, Yujie Liu, Xiuyu Chen, Shihua Zhao   +13 more
doaj   +1 more source

Incremental Diagnostic Value of Right Ventricular Strain Analysis in Arrhythmogenic Right Ventricular Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Strain analysis is a sensitive method for the assessment of ventricular structural or functional alterations. The authors aimed to determine whether right ventricular (RV) strain parameters can discriminate patients with revised Task Force ...
Zhixiang Dong, Xuan Ma, Jiaxin Wang, Shujuan Yang, Shiqin Yu, Yanyan Song, Yun Tang, Xiaorui Xiang, Kai Yang, Kankan Zhao, Minjie Lu, Xiuyu Chen, Shihua Zhao   +12 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Risk stratification and outcomes in diabetes mellitus patients with preserved ejection fraction: a cardiac MRI study

BMC Medicine
Background Patients with diabetes mellitus (DM) have a significantly increased risk of developing heart failure (HF), which exacerbates adverse cardiovascular outcomes. Limited data are available on the prognostic value of cardiac MRI in DM.
Wenjing Yang, Mengdi Jiang, Huaying Zhang, Di Zhou, Yining Wang, Leyi Zhu, Zhaoxin Tian, Gang Yin, Qiang Zhang, Arlene Sirajuddin, Andrew E. Arai, Shihua Zhao, Minjie Lu   +12 more
doaj   +1 more source

Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park, Emily J. Koubek, Richard Beare, Lynn Ang, Brian C. Callaghan, Rodica Pop‐Busui, Eva L. Feldman, Evan L. Reynolds   +7 more
wiley   +1 more source